Enzyme Multiplied Immunoassay Technique

The Enzyme Multiplied Immunoassay Technique, or EMIT, is a common method for screening urine and blood for drugs, whether legal or illicit. It is part of the homogeneous immunoassay.The technique is relatively nonspecific compared to some other analysis methods, such as mass spectrometry, but has the advantage of being fast and inexpensive. It has, however, been shown in some cases to be somewhat inaccurate in its findings. The patent for EMIT technology is owned by the Syva Corporation of Palo Alto, CA. In March of 2005, the patent for EMIT technology was sold for an undislosed price to the ORAK Corp, which is based in San Francisco. (From the Wikpedia article Enzyme Multiplied Immunoassay Technique.)

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Recent Publications on Enzyme Multiplied Immunoassay Technique:
Regulatory effect of FK506 on CD152 and PD-1 in the liver allorecipients. AIM: We dynamically observed the expression of CD152 and PD-1 on T-cell...	5th September, 2008	Division of Clinical Immunological Laboratory, West China Hospital of	Transplant Proc. 2008 Jun;40(5):1495-7. DOI Direct Link
Relative proportions of serum carbamazepine and its pharmacologically active 10,11-epoxy derivative: effect of polytherapy and renal insufficiency. BACKGROUND: The proposed action mechanism and pharmacological activity of...	12th August, 2008	Unidad Monitorizacion Farmacos, Laboratorio Central, Hospital Clinico	Ups J Med Sci. 2008;113(2):171-80.
Quantification of cyclosporine and tacrolimus in whole blood. Comparison of liquid chromatography-electrospray mass spectrometry with the enzyme multiplied immunoassay technique. OBJECTIVES: The aim of this work was to compare a validated liquid...	7th August, 2008	Laboratory Medicine Service, University Hospitals of Geneva, Geneva,	Clin Biochem. 2008 Jul;41(10-11):910-3. Epub 2008 Mar 12. DOI Direct Link
Comparison of high-performance liquid chromatography and enzyme-multiplied immunoassay technique to monitor mycophenolic acid in paediatric renal recipients. Therapeutic drug monitoring (TDM) of mycophenolate mofetil (MMF) is...	3rd July, 2008	Department of Paediatric Pharmacology and Pharmacogenetics, Hopital Robert	Pediatr Nephrol. 2008 Oct;23(10):1859-65. Epub 2008 Jul 2. DOI Direct Link
Incorrect alphabits. BACKGROUND: The proposed action mechanism and pharmacological activity of...	2nd July, 2008		MLO Med Lab Obs. 2008 Apr;40(4):8; discussion 8.
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Enzyme Multiplied Immunoassay Technique Patents:
US Patent No.	Title
6800460	Mammalian cytokine complexes
7022492	Ecstasy haptens and immunogens
7025962	Mammalian cell surface antigens; related reagents
7034137	Isolated mammalian membrane protein genes; related reagents
7060800	Antibodies binding the TNF related protein, TNF-X
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