Factor Ixa

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Recent Publications on Factor Ixa:
A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor. BACKGROUND: Active and safe reversibility of anticoagulation is an unmet...	9th July, 2008	Duke Clinical Research Institute, Durham, NC 27705, USA.	J Thromb Haemost. 2008 May;6(5):789-96. Epub 2008 Feb 18. DOI Direct Link
Effects of apoptosis and lipid peroxidation on T-lymphoblastoid phospholipid-dependent procoagulant activity. BACKGROUND: Coagulation has an absolute requirement for macromolecular...	8th July, 2008	Biotherapeutics Group, National Institute for Biological Standards and	J Thromb Haemost. 2008 Jul;6(7):1122-30. DOI Direct Link
Identification of a plasmin-interactive site within the A2 domain of the factor VIII heavy chain. Factor VIII is activated and inactivated by plasmin by limited...	3rd July, 2008	Department of Pediatrics, Nara Medical University, Kashihara, Nara	Biochim Biophys Acta. 2008 May;1784(5):753-63. Epub 2008 Feb 14. DOI Direct Link
Mild/moderate haemophilia A: new insights into molecular mechanisms and inhibitor development. In mild/moderate haemophilia A (MHA) patients, many factor VIII (FVIII)...	25th June, 2008	Centre de traitement pour Hemophiles AP-HP Hopital Bicetre, Universite	Haemophilia. 2008 Jul;14 Suppl 3:138-46. DOI Direct Link
Partial factor IXa inhibition with TTP889 for prevention of venous thromboembolism: an exploratory study. BACKGROUND: Inhibitors of factor (F) IXa show potent antithrombotic...	18th June, 2008	Sahlgrenska University Hospital/Ostra, Goteborg, Sweden.	J Thromb Haemost. 2008 Mar;6(3):457-63. Epub 2007 Dec 12. DOI Direct Link
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BioNews Results for Factor Ixa:
Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation Syst	PR Newswire via Yahoo!:  Jun 5 2008 11:46AM Matching: factor ixa
Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation Syst	Yahoo! Canada:  Jun 5 2008 11:40AM Matching: factor ixa
::: Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation	Biotech Intelligence:  Jun 5 2008 12:37PM Matching: factor ixa
Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation Syst	Digital CAD:  Jun 5 2008 12:35PM Matching: factor ixa
Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation Syst	Calibre Macro World:  Jun 5 2008 11:38AM Matching: factor ixa
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Factor Ixa Clinical Trials:
Safety and Dosing Evaluation of REG1 Anticoagulation System	Healthy Intervention: Drug: REG1

Factor Ixa Patents:
US Patent No.	Title
7250415	1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, .beta.-aminoacids, .alpha.-aminoacids and derivatives thereof as factor Xa inhibitors
7300922	Modulators of pharmacological agents
7304041	Modulators of coagulation factors
7308303	Thrombolysis and chronic anticoagulation therapy
7312214	1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
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