Factor Xia

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Recent Publications on Factor Xia:
Clavatadine A, A Natural Product with Selective Recognition and Irreversible Inhibition of Factor XIa. Bioassay-guided fractionation of a CH 2Cl 2/MeOH extract of the sponge...	31st May, 2008		J Med Chem. 2008 May 30;. DOI Direct Link
A catalytic domain exosite (Cys527-Cys542) in factor XIa mediates binding to a site on activated platelets. The zymogen, factor XI, and the enzyme, factor XIa, interact specifically...	31st May, 2008	Sol Sherry Thrombosis Research Center and Department of Biochemistry,	Biochemistry. 2007 Dec 18;46(50):14450-60. Epub 2007 Nov 17. DOI Direct Link
Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation. Factor XI is the zymogen of a dimeric plasma protease, factor XIa, with...	21st May, 2008	Department of Pathology, Vanderbilt University, Nashville, Tennessee	J Biol Chem. 2008 Mar 14;283(11):6696-705. Epub 2008 Jan 11. DOI Direct Link
A renaissance for the contact system in blood coagulation? Protein Z (PZ) is a plasma vitamin K-dependent protein that functions as a...	16th May, 2008		Thromb Haemost. 2008 Mar;99(3):457-60.
Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin and factor XIa. Coagulation factor XI (FXI) is a covalent homodimer consisting of two...	29th April, 2008	Sol Sherry Thrombosis Research Center, Temple University School of	J Biol Chem. 2008 Apr 25;. DOI Direct Link
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BioNews Results for Factor Xia:
New Role Of Inflammatory Protein In Polycycstic Kidney Disease Identified, Could Lead To Treatment	Science Daily:  Jun 21 2008 1:11AM Matching: factor xia
Rong Li Lab Identifies New Role of Inflammatory Protein in Polycystic Kidney Disease and a Possible Treatment	Innovations Report:  Jun 19 2008 4:58PM Matching: factor xia
Innovative integrated system for real-time measurement of hybridization and melting on standard format microar	Bio Techniques:  Jun 5 2008 12:49AM Matching: factor xia
Pharmaceutical preparations and medicine capable of generating and/or containing thrombin	PharmCast:  May 28 2008 3:55AM Matching: factor xia
Gene therapy agent for Haemophilia B and its preparation method	PharmCast:  May 6 2008 8:36PM Matching: factor xia
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Factor Xia Patents:
US Patent No.	Title
7135469	Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors
7211671	Substituted 1,3-dihydro-imidazol-2-one and 1,3-dihydro-imidazol-2-thione derivatives as inhibitors of matrix metalloproteinases and/or TNF-.alpha. converting enzyme (TACE)
7214479	E. coli O157:H7 C1-INH-binding protein and methods of use
7217794	Compounds and methods for treatment of thrombosis
7220569	Nucleic acids encoding factor X analogues having a modified protease cleavage site
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