Factor Xiia

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Recent Publications on Factor Xiia:
Lower factor XII activity is a risk marker rather than a risk factor for cardiovascular disease: a rebuttal. Coagulation factor XI (FXI) is a covalent homodimer consisting of two...	25th September, 2008		J Thromb Haemost. 2008 Jun;6(6):1053-4; author reply 1055-6. Epub 2008 Mar DOI Direct Link
The kallikrein-kinin system in diabetic retinopathy: lessons for the kidney. Diabetic retinopathy and diabetic nephropathy are common microvascular...	30th August, 2008	Department of Medicine, Harvard Medical School and Research Division,	Kidney Int. 2008 May;73(10):1114-9. Epub 2008 Feb 13. DOI Direct Link
Adrenomedullary catecholamine, pressor and chronotropic responses to human coagulation beta-FXIIa mediated by endogenous kinins. OBJECTIVES: There is increasing evidence that blood coagulation factors...	30th August, 2008	University Health Network and Mount Sinai Hospital Division of Cardiology,	J Hypertens. 2008 Jan;26(1):61-9. DOI Direct Link
Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIa. Coagulation factor XI (FXI) is a covalent homodimer consisting of two...	20th August, 2008	Sol Sherry Thrombosis Research Center, Temple University School of	J Biol Chem. 2008 Jul 4;283(27):18655-64. Epub 2008 Apr 25. DOI Direct Link
Biological activities of C1 inhibitor. Broadly speaking, C1 inhibitor plays important roles in the regulation of...	5th August, 2008	Harvard Medical School, Immune Disease Institute, 800 Huntington Avenue,	Mol Immunol. 2008 Jul 30. DOI Direct Link
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BioNews Results for Factor Xiia:
Factor IXa for the treatment of bleeding disorders	PharmCast:  Sep 30 2008 3:50AM Matching: factor xiia

Factor Xiia Clinical Trials:
Risk Markers in the Acute Coronary Syndromes	Risk Assessment;   Chest Pain;   Coronary Artery Disease;   Unstable Angina Pectoris;   Myocardial Infarction

Factor Xiia Patents:
US Patent No.	Title
7208266	Endogenous coagulation activator compounds --use in exploring endogenous coagulation
7265084	Glycopegylation methods and proteins/peptides produced by the methods
7265085	Glycoconjugation methods and proteins/peptides produced by the methods
7265121	Chemical compounds
7273722	Neurotoxins with enhanced target specificity
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