G-Protein-Coupled Receptor Kinase 2

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Recent Publications on G-Protein-Coupled Receptor Kinase 2:
G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure. Myocardial G protein-coupled receptor kinase (GRK)2 is a critical...	19th July, 2008	George Zallie and Family Laboratory for Cardiovascular Gene Therapy, and	Circ Res. 2008 Jul 17;. DOI Direct Link
G protein-coupled receptor kinase 2 (GRK2) in migration and inflammation. G protein-coupled receptor kinase 2 (GRK2) is a key modulator of G...	12th July, 2008	Departamento de Biologia Molecular and Centro de Biologia Molecular	Arch Physiol Biochem. 2008 Jul;114(3):195-200. DOI Direct Link
Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity. We recently reported that the upregulation of adrenal G protein-coupled...	4th July, 2008	Center for Translational Medicine and George Zallie and Family Laboratory	Mol Ther. 2008 Feb;16(2):302-7. Epub 2007 Nov 27. DOI Direct Link
Minocycline provides protection against beta-amyloid(25-35)-induced alterations of the somatostatin signaling pathway in the rat temporal cortex. Minocycline is a semi-synthetic second-generation tetracycline known to...	17th June, 2008	Departamento de Endocrinologia, Hospital Infantil Universitario Nino	Neuroscience. 2008 Jul 17;154(4):1458-66. Epub 2008 Apr 29. DOI Direct Link
SELECTIVE REGULATION OF H1 HISTAMINE RECEPTOR SIGNALING BY G PROTEIN-COUPLED RECEPTOR KINASE 2 IN UTERINE SMOOTH MUSCLE CELLS. Histamine stimulates uterine contraction, however little is known...	31st May, 2008	Reproductive Sciences Section, Department of Cancer Studies and Molecular	Mol Endocrinol. 2008 May 29;. DOI Direct Link
→View more research publications.

G-Protein-Coupled Receptor Kinase 2 Clinical Trials:
Measuring G Protein-Coupled Receptor Kinase-2 (GRK2) in the Blood to Diagnose and Treat Patients With Heart Failure	Heart Failure

G-Protein-Coupled Receptor Kinase 2 Patents:
US Patent No.	Title
7348305	Inhibitor of cardiac tachyarrhythmias
7241812	Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
7214496	Modified G-protein coupled receptors
6579709	Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof

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