Recent Publications on G-Protein-Coupled Receptor Kinase 3: |  |
| [The Arg16Glybeta2-adrenergic receptor polymorphism influences long term clinical responses to beta2-agonist]
| 18th September, 2008
| Department of Respiratory Medicine, Hokkaido University School of Graduate
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Selective regulation of H1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells.
Histamine stimulates uterine contraction; however, little is known...
Direct Link | 11th September, 2008
| Reproductive Sciences Section, Department of Cancer Studies and Molecular
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Clinically responsible genetic testing in neuropsychiatric patients: a bridge too far and too soon.
Earlier studies identified the dynorphin-kappa opioid receptor (KOR)...
Direct Link | 5th September, 2008
| University of California, San Diego, School of Medicine, Department of
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Repeated swim stress induces kappa opioid-mediated activation of extracellular signal-regulated kinase 1/2.
Earlier studies identified the dynorphin-kappa opioid receptor (KOR)...
Direct Link | 4th September, 2008
| Department of Pharmacology, University of Washington, Seattle, Washington,
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Promoter variant in the GRK3 gene associated with bipolar disorder alters gene expression.
BACKGROUND: We have previously reported a single nucleotide polymorphism...
Direct Link | 16th August, 2008
| Department of Psychiatry, University of California, San Diego, CA 92093,
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Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness.
G protein-coupled receptor kinase-2 and -3 (GRK2 and GRK3) in cardiac...
Direct Link | 11th June, 2008
| Institute for Surgical Research, University of Oslo and
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Proteasome inhibition 1 h following ischemia protects GRK2 and prevents malignant ventricular tachyarrhythmias and SCD in a model of myocardial infarction.
Arrhythmia-prone epicardial border zone (EBZ) tissues demonstrate...
Direct Link | 16th May, 2008
| Endocrinology Division, University of Oklahoma Health Sciences Center and
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Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling.
Leukocytes from individuals with warts, hypogammaglobulinemia, infections,...
Direct Link | 23rd April, 2008
| INSERM U819, Paris, France.
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Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation.
Dopamine and other G protein-coupled receptors (GPCRs) represent the major...
Direct Link | 23rd April, 2008
| Department of Pharmacology, Vanderbilt University Medical Center, Preston
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Effects of chronic desipramine treatment on alpha2-adrenoceptors and mu-opioid receptors in the guinea pig cortex and hippocampus.
The existence of a close relation between presynaptic inhibitory...
Direct Link | 16th April, 2008
| Clinical and Applied Pharmacology Centre, University of Insubria and
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Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
Dysregulation of dopamine (DA) receptors is believed to underlie...
Direct Link | 28th March, 2008
| Department of Pharmacology, Vanderbilt University Medical Center,
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The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment.
BACKGROUND: In addition to the regulation of blood pressure, alpha2- and...
Direct Link | 15th March, 2008
| Research Center for Cardiovascular Diseases, Brown Foundation Institute of
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Roles of c-Src in alpha1B-adrenoceptor phosphorylation and desensitization.
1 The role of the protein tyrosine kinase, c-Src, on the function and...
Direct Link | 22nd February, 2008
| Departamento de Biologia Celular, Instituto de Fisiologia Celular,
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Science and commerce. Gene tests for psychiatric risk polarize researchers.
1 The role of the protein tyrosine kinase, c-Src, on the function and...
Direct Link | 1st February, 2008
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Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation.
OBJECTIVES: Two genome-wide linkage surveys suggest chromosome 22q12 may...
Direct Link | 1st February, 2008
| Department of Psychiatry, University of California at San Diego, San Diego
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