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G-Protein-Coupled Receptor Kinase 5

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Recent Publications on G-Protein-Coupled Receptor Kinase 5:

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GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice.
BACKGROUND: Deficiency of membrane G-protein coupled receptor (GPCR)...		22nd August, 2008
Lab, for Alzheimer's Disease & Aging Res,, VA Med, Center, Kansas City, MO J Neuroinflammation. 2008 Jun 3;5:24.
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Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.
G protein-coupled receptor (GPCR) kinases (GRKs) are critical regulators...		20th August, 2008
George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12457-62. Epub 2008 Aug 18.
DOI Direct Link
Beta-adrenergic signaling in heart failure-adapt or die.
BACKGROUND: Deficiency of membrane G-protein coupled receptor (GPCR)...		18th July, 2008
Nat Med. 2008 May;14(5):485-7.
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A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.
Beta-adrenergic receptor (betaAR) blockade is a standard therapy for...		18th July, 2008
Department of Internal Medicine, University of Cincinnati, 231 Albert Nat Med. 2008 May;14(5):510-7. Epub 2008 Apr 20.
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Phosphorylation of the beta2-adrenergic receptor in plasma membranes by intrinsic GRK5.
Characterization of the GRKs participating in the phosphorylation of the...		31st May, 2008
The University of Texas Health Science Center Houston, P.O Box 20708, Biochemistry. 2007 Dec 18;46(50):14438-49. Epub 2007 Nov 23.
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G-Protein-Coupled Receptor Kinase 5 Patents:

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US Patent No.Title
7365178 Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
7198776 Metal complex compounds

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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