G-Protein-Coupled Receptor Kinases

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Recent Publications on G-Protein-Coupled Receptor Kinases:
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging. Inclusions in the brain containing alpha-synuclein are the pathological...	13th June, 2008	Department of Genetics, University Medical Centre Groningen and University	PLoS Genet. 2008 Mar 21;4(3):e1000027. DOI Direct Link
Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages. G-protein coupled receptor kinases (GRKs) and arrestins (ARRs) are...	6th June, 2008	Department of Physiology, Division of Pathology, Michigan State	Mol Immunol. 2008 Apr;45(8):2312-22. Epub 2008 Jan 4. DOI Direct Link
SELECTIVE REGULATION OF H1 HISTAMINE RECEPTOR SIGNALING BY G PROTEIN-COUPLED RECEPTOR KINASE 2 IN UTERINE SMOOTH MUSCLE CELLS. Histamine stimulates uterine contraction, however little is known...	31st May, 2008	Reproductive Sciences Section, Department of Cancer Studies and Molecular	Mol Endocrinol. 2008 May 29;. DOI Direct Link
Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease. The identification and characterization of the processes of G...	16th May, 2008	Department of Laboratory Medicine and Pathobiology, Banting Institute,	Methods Mol Biol. 2008;448:77-107. DOI Direct Link
Beta-arrestins: multifunctional cellular mediators. Initially thought to play a role only in G-protein-coupled receptor...	30th April, 2008	Department of Biology, University of Haifa, Israel.	Physiology (Bethesda). 2008 Feb;23:17-22. DOI Direct Link
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G-Protein-Coupled Receptor Kinases Clinical Trials:
Measuring G Protein-Coupled Receptor Kinase-2 (GRK2) in the Blood to Diagnose and Treat Patients With Heart Failure	Heart Failure

G-Protein-Coupled Receptor Kinases Patents:
US Patent No.	Title
7384755	Cell-based assay for G-protein-coupled receptor-mediated activity employing a mutated cyclic nucleotide-gated ion channel and a membrane potential dye
6953673	Histamine H2 receptor and uses
6893827	Receptor function assay for G-protein coupled receptors and orphan receptors by reporter enzyme mutant complementation
6833439	IP-10/MIG receptor designated CXCR3, nucleic acids and methods of use therefor
6833436	Short peptides which selectively modulate the activity of serine/threonine kinases
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