Recent Publications on G-Protein-Coupled Receptor Kinases: |  |
Different kinases desensitize the human delta-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists.
In a previous work, we described a differential desensitization of the...
Direct Link | 30th September, 2008
| Universite de Caen, Laboratoire de biologie moleculaire et cellulaire de
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Phosphorylation of GRK7 by PKA in cone photoreceptor cells is regulated by light.
The retina specific G protein-coupled receptor kinases, GRK1 and GRK7,...
Direct Link | 23rd September, 2008
| Department of Cell and Developmental Biology, The University of North
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Dual role of the beta 2-adrenergic receptor C-terminus for the binding of beta -arrestin and receptor internalization.
Homologous desensitization of beta(2)-adrenergic and other G...
Direct Link | 20th September, 2008
| School of Pharmacy, University of Reading, Reading, Berkshire RG6 6AJ.
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Selective regulation of H1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells.
Histamine stimulates uterine contraction; however, little is known...
Direct Link | 11th September, 2008
| Reproductive Sciences Section, Department of Cancer Studies and Molecular
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Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis.
G-protein-coupled receptor kinases (GRKs) comprise a family of seven...
Direct Link | 4th September, 2008
| Department of Diagnostic Pathology, Tokyo Medical University, Tokyo,
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GPCR signalling in hypertension: role of GRKs.
Hypertension is a prevalent condition in the developed world and disease...
Direct Link | 12th August, 2008
| Eugene Feiner Laboratory for Vascular Biology and Thrombosis, Center for
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G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia.
Post-inflammatory pain is a poorly understood phenomenon. G...
Direct Link | 9th August, 2008
| Laboratory of Psychoneuroimmunology, University Medical Center Utrecht,
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GRK2-dependent desensitization downstream of G proteins.
G protein-coupled receptor kinases (GRKs) are serine/threonine kinases...
Direct Link | 2nd August, 2008
| Departamento de Biologia Molecular and Centro de Biologia Molecular
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A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.
Beta-adrenergic receptor (betaAR) blockade is a standard therapy for...
Direct Link | 18th July, 2008
| Department of Internal Medicine, University of Cincinnati, 231 Albert
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Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas.
Somatostatin acts at five G protein-coupled receptors, sst(1)-sst(5). In...
Direct Link | 16th July, 2008
| Department of Environmental Sciences, University of Tuscia, Largo
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A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of beta2-adrenergic receptors.
Beta-agonist treatment of asthma displays substantial interindividual...
Direct Link | 16th July, 2008
| Cardiopulmonary Genomics Program, Department of Medicine, University of
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Phosphorylation of group I metabotropic glutamate receptors (mGluR1/5) in vitro and in vivo.
Group I metabotropic glutamate receptors (mGluR1 and mGluR5 subtypes) are...
Direct Link | 1st July, 2008
| Department of Basic Medical Science, School of Medicine, University of
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Eliminating phosphorylation sites of the parathyroid hormone receptor type 1 differentially affects stimulation of phospholipase C and receptor internalization.
The parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor (PTH1R)...
Direct Link | 26th June, 2008
| Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114,
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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging.
Inclusions in the brain containing alpha-synuclein are the pathological...
Direct Link | 13th June, 2008
| Department of Genetics, University Medical Centre Groningen and University
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Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease.
The identification and characterization of the processes of G...
Direct Link | 16th May, 2008
| Department of Laboratory Medicine and Pathobiology, Banting Institute,
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