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G-Quadruplexes

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Recent Publications on G-Quadruplexes:

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Potassium-Lead-Switched G-Quadruplexes: A New Class of DNA Logic Gates.
A cation-driven allosteric G-quadruplex DNAzyme (PW17) was utilized to...
19th November, 2009
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute J Am Chem Soc. 2009 Oct 28;131(42):15082-15083.
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Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology.
Recently, it has been shown that in K(+) solution the human telomeric...
31st October, 2009
Division of Physics and Applied Physics, School of Physical and J Am Chem Soc. 2009 Nov 25;131(46):16824-16831.
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Cation localization and movement within DNA thrombin binding aptamer in solution.
The thrombin binding aptamer, 15-mer oligonucleotide...
30th October, 2009
Slovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, Org Biomol Chem. 2009 Nov 21;7(22):4677-84. Epub 2009 Sep 21.
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Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA.
Large numbers of guanine-rich sequences with potential to form...
28th October, 2009
Laboratory of Biochemistry and Biophysics, College of Life Sciences, Wuhan Nucleic Acids Res. 2009 Oct 25.
DOI Direct Link
Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.
In the past decade, DNA G-quadruplexes have come into the limelight thanks...
28th October, 2009
Dipartimento di Chimica Farmaceutica e Tossicologica, Universita degli J Am Chem Soc. 2009 Nov 18;131(45):16336-7.
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G-Quadruplexes Patents:

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US Patent No.Title
7601769 Multilayered chromonic structures
6858608 Chemical derivatives and their application as antitelomerase agents
6696565 Method and associated pyrimido[4,5-d]pyrimidine-2,5-diones and pyrido[4,3-d]pyrimidin-2-ones for forming nanotubes
6689887 Inhibition of human telomerase by a G-quadruplex-interaction compound
6645964 Chemical derivatives and their application as antitelomerase agent

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BioPortfolio Ltd. offers e-mail and postal lists for G-Quadruplexes scientists - we have details of around 48 individuals working on G-Quadruplexes .


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