Recent Publications on G-Quadruplexes: |  |
G-quadruplexes: the beginning and end of UTRs.
Molecular mechanisms that regulate gene expression can occur either before...
Direct Link | 4th October, 2008
| Cavendish Laboratory, University of Cambridge, JJ Thompson Ave, Cambridge
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Diverse Polymorphism of G-Quadruplexes as a Kinetic Phenomenon.
Knowledge of forces that drive conformational transitions of...
Direct Link | 2nd October, 2008
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Selective recognition of a DNA G-quadruplex by an engineered antibody.
Particular guanine rich nucleic acid sequences can fold into stable...
Direct Link | 26th September, 2008
| The University Chemical Laboratory, University of Cambridge, Lensfield
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Site-specific self-cleavage of G-quadruplexes formed by human telemetric repeats.
It is demonstrated in our investigations that certain G-quadruplex...
Direct Link | 25th September, 2008
| Division of Chemistry and Biological Chemistry, School of Physical and
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Assembling of G-strands into novel tetra-molecular parallel G4-DNA nanostructures using avidin-biotin recognition.
We describe a method for the preparation of novel long (hundreds of...
Direct Link | 17th September, 2008
| Department of Biochemistry, George S. Wise Faculty of Life Sciences, Tel
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The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer.
The fragile X mental retardation protein (FMRP) is a RNA-binding protein...
Direct Link | 17th September, 2008
| IGBMC (Institut de Genetique et de Biologie Moleculaire et Cellulaire),
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G-quadruplex recognition by bis-indole carboxamides.
Herein we report the de novo design and synthesis of a geometrically...
Direct Link | 10th September, 2008
| Department of Chemistry, University of Cambridge, Lensfield Road,
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Ligand binding to tetra-end-linked (TGGGGT)4 G-quadruplexes: an electrospray mass spectroscopy study.
The binding properties of a series of known G-quadruplex ligands have been...
Direct Link | 9th September, 2008
| Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di
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Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.
The promoter of the KRAS proto-oncogene contains a critical nuclease...
Direct Link | 9th September, 2008
| Department of Biomedical Science and Technology, School of Medicine, P.le
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G-quadruplex forming oligonucleotides as finely tunable aptamers: towards better DNA mimics.
The intense search for oligonucleotides (ODNs) endowed with...
Direct Link | 9th September, 2008
| Dipartimento di Chimica Organica e Biochimica, Universita degli Studi di
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Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA.
Here, we report the first example that one enantiomer of a supramolecular...
Direct Link | 9th September, 2008
| Division of Biological Inorganic Chemistry, Key Laboratory of Rare Earth
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| G-quadruplex structure: a target for anticancer therapy and a probe for detection of potassium.
| 9th September, 2008
| Bioengineering Institute of Life Science Department, Zhejiang Sci-Tech
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Stability and cations coordination of DNA and RNA 14-mer g-quadruplexes: a multiscale computational approach.
Molecular dynamics simulations have been used to study the differences...
Direct Link | 5th September, 2008
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A new method for the study of G-quadruplex ligands.
A new method for the study of G-quadruplex ligands was developed, in which...
Direct Link | 19th August, 2008
| Key Laboratory of Functional Polymer Materials, Ministry of Education,
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Structure determination of an interstrand-type cis-anti cyclobutane thymine dimer produced in high yield by UVB light in an oligodeoxynucleotide at acidic pH.
UVB irradiation of DNA produces photodimers in adjacent DNA bases and on...
Direct Link | 6th August, 2008
| Department of Chemistry, Washington University, St. Louis, Missouri 63130,
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