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Galactosylceramidase

Galactosylceramidase is an enzyme which removes galactose from ceramide derivatives . (From the Wikpedia article Galactosylceramidase.)

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Recent Publications on Galactosylceramidase:
Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides. Sulfatides, possible antithrombotic factors belonging to...	10th November, 2009	Department of Metabolic Regulation, Institute on Aging and Adaptation,	Biochem Biophys Res Commun. 2009 Nov 4. DOI Direct Link
Pathogenesis of leukodystrophy for Krabbe disease: molecular mechanism and clinical treatment. We reported the basic concept of the pathology of leukodystrophy with...	23rd September, 2009	Department of Pediatrics, Osaka University Graduate School of Medicine,	Brain Dev. 2009 Aug;31(7):485-7. Epub 2009 Mar 29. DOI Direct Link
Diffusion tensor imaging detects axonal injury and demyelination in the spinal cord and cranial nerves of a murine model of globoid cell leukodystrophy. Globoid cell leukodystrophy is an inherited neurodegenerative disorder...	4th August, 2009	Department of Radiology, Washington University School of Medicine, St.	NMR Biomed. 2009 Jul 31. DOI Direct Link
Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease. This study characterized the therapeutic benefits of combining...	31st July, 2009	Department of Anatomy and Cell Biology, College of Medicine, University of	J Neurosci Res. 2009 Jun;87(8):1748-59. DOI Direct Link
Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture. Lipid rafts (LRs) are membrane realms characterized by high concentrations...	29th May, 2009	Department of Anatomy and Cell Biology, College of Medicine, University of	J Neurosci. 2009 May 13;29(19):6068-77. DOI Direct Link
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Galactosylceramidase Patents:
US Patent No.	Title
6730297	Use of recombinant gene delivery vectors for treating or preventing lysosomal storage disorders
7122354	Nucleic acid encoding a chimeric polypeptide
7125843	Glycoconjugates including more than one peptide
7138371	Remodeling and glycoconjugation of peptides
7157277	Factor VIII remodeling and glycoconjugation of Factor VIII
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

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Galactosylceramidase

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Recent Publications on Galactosylceramidase:

Galactosylceramidase Patents: