Recent Publications on Gamma-Butyrobetaine Dioxygenase: |  |
| Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice.
| 2nd September, 2008
| Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho
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Clofibrate treatment up-regulates novel organic cation transporter (OCTN)-2 in tissues of pigs as a model of non-proliferating species.
Recent studies have shown that treatment of rodents with agonists of...
Direct Link | 28th May, 2008
| Institute of Agricultural and Nutritional Sciences,
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PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis.
We tested the hypothesis that transcription of novel organic cation...
Direct Link | 16th April, 2008
| Institute of Agricultural and Nutritional Sciences,
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Treatment with pharmacological peroxisome proliferator-activated receptor alpha agonist clofibrate causes upregulation of organic cation transporter 2 in liver and small intestine of rats.
Activation of PPARalpha by clofibrate has recently been shown to cause...
Direct Link | 2nd November, 2007
| Institut fur Agrar- und Ernahrungswissenschaften,
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PPAR alpha-activation results in enhanced carnitine biosynthesis and OCTN2-mediated hepatic carnitine accumulation.
In fasted rodents hepatic carnitine concentration increases considerably...
Direct Link | 16th October, 2007
| Department of Clinical Chemistry, Academic Medical Center, University of
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Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction.
The inhibition of gamma-butyrobetaine (GBB) hydroxylase, a key enzyme in...
Direct Link | 19th June, 2007
| Latvian Institute of Organic Synthesis, Riga, Latvia.
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Genomic structure, alternative maturation and tissue expression of the human BBOX1 gene.
Gamma-butyrobetaine hydroxylase (BBOX1) is the enzyme responsible for the...
Direct Link | 30th January, 2007
| Inserm - CRI-Dijon, University of Dijon, UFR Sciences Vie, 6 Blvd.
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Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat.
Although the mouse frequently is used to study metabolism and deficiencies...
Direct Link | 13th October, 2006
| Department of Clinical Chemistry, Academic Medical Center, University of
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L-carnitine is synthesized in the human fetal-placental unit: potential roles in placental and fetal metabolism.
Carnitine plays an indispensable role in fatty acid oxidation. Previous...
Direct Link | 31st August, 2006
| Department of Pediatrics, Academic Medical Center, University of
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| Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats.
| 1st June, 2005
| Department of Surgery, Michigan State University, Grand Rapids, MI, USA.
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| Liver L-carnitine biosynthesis in non-pregnant, pregnant and lactating rabbits.
| 10th August, 2004
| Kirikkale State Hospital, Department of Clinical Biochemistry, Kirikkale,
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