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Gangliosidoses

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Recent Publications on Gangliosidoses:
Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. Increased expression of gangliosides by different tumor types including...	11th November, 2009	Department of Immunology, Lerner Research Institute, Cleveland Clinic	J Immunol. 2009 Oct 15;183(8):5050-8. DOI Direct Link
Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosis. Sandhoff disease is a progressive neurodegenerative disorder caused by...	7th November, 2009	Health Technology Research Center, National Institute of Advanced	J Neurochem. 2009 Nov;111(4):1031-41. Epub 2009 Sep 18. DOI Direct Link
Substrate reduction therapy in juvenile GM2 gangliosidosis. Substrate reduction therapy (SRT) is considered to be a potential...	6th November, 2009	Div. of Clinical and Metabolic Genetics, Hospital for Sick Children, Ont.,	Mol Genet Metab. 2009 Sep-Oct;98(1-2):215-24. Epub 2009 Jun 12. DOI Direct Link
Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis. GM2 gangliosidosis (GM2g) is an inherited neurodegenerative disorder...	12th September, 2009	Division of Clinical and Metabolic Genetics, Hospital for Sick Children,	Mol Genet Metab. 2009 Aug;97(4):284-91. Epub 2009 May 3. DOI Direct Link
Critical role of iron in the pathogenesis of the murine gangliosidoses. Neurodegeneration is a prominent feature of the gangliosidoses, a group of...	18th August, 2009	Department of Pharmacology, University of Oxford, Mansfield Road, Oxford	Neurobiol Dis. 2009 Jun;34(3):406-16.
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Gangliosidoses Patents:
US Patent No.	Title
6926898	Albumin fusion proteins
7175988	Human G-protein Chemokine Receptor (CCR5) HDGNR10
7189690	Albumin fusion proteins
7196164	Secreted protein HHTLF25
7205139	Tissue plasminogen activator-like protease
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Gangliosidoses

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Recent Publications on Gangliosidoses:

Gangliosidoses Patents: