Gangliosidoses

Download PDF

Recent Publications on Gangliosidoses:
Juvenile-onset G(M2)-gangliosidosis in an African-American child with nystagmus. G(M2)-gangliosidosis is a neurodegenerative lysosomal disease with several...	11th July, 2008	Division of Human Genetics, Department of Genetics and Developmental	Pediatr Neurol. 2008 Apr;38(4):284-6. DOI Direct Link
Hexosaminidase assays. beta-Hexosaminidases (EC 3.2.1.52) are lysosomal enzymes that remove...	14th May, 2008	LIMES, Membrane Biology and Lipid Biochemistry Unit, c/o Kekule-Institut	Glycoconj J. 2008 May 13;. DOI Direct Link
Increased hexosaminidase activity in antipsychotic-induced extrapyramidal side effects: Possible association with higher occurrence in bipolar disorder patients. Dystonic movements and Parkinsonism are frequently seen in gangliosidoses...	26th April, 2008	Dokuz Eylul University, Medical School, Izmir, Turkey.	Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1214-20. Epub DOI Direct Link
An exposed carboxyl group on sialic acid is essential for gangliosides to inhibit calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase: relevance to gangliosidoses. We previously observed that gangliosides GM2, GM1, and GM3 inhibit...	19th February, 2008	Department of Biological Chemistry, Weizmann Institute of Science,	J Neurochem. 2008 Jan;104(1):140-6. DOI Direct Link
[Neurological presentations of lysosomal diseases in adult patients] Lysosomal diseases represent a large group of genetic storage disorders...	17th January, 2008	Federation des maladies du systeme nerveux et centre de reference national	Rev Neurol (Paris). 2007 Oct;163(10):919-29. DOI Direct Link
→View more research publications.

Gangliosidoses Clinical Trials:
Pharmacokinetics and Tolerability of Zavesca® (Miglustat) In Patients With Juvenile GM2 Gangliosidosis	Gangliosidoses GM2

Gangliosidoses Patents:
US Patent No.	Title
6566099	Nucleic acid encoding a chimeric polypeptide
6919433	Antibodies to protein HPMBQ91
6926898	Albumin fusion proteins
6936688	Human chemokine beta-10 mutant polypeptides
6936691	Secreted protein HCE3C63
→View more patents.

BioPortfolio Ltd. offers e-mail and postal lists for Gangliosidoses scientists - we have details of around 70 individuals working on Gangliosidoses .

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.  See User Agreement

Send comments and feedback to:
Peter Barfoot Managing Director, BioPortfolio Ltd.
UK Tel: (+44) 1300 321501
USA Voicemail and Fax: (+1) 415 680 2472

All rights reserved. All other trademarks recognized.

BioPortfolio Limited is registered in England & Wales at Wessex Barn, Dorchester Road, Frampton, Dorset, DT2 9NB, UK. No.3312883 VAT No. GB 744 6483 10

Copyright 1997-2008 - BioPortfolio Limited.