Gangrene

Gangrene is a complication of necrosis characterized by the decay of body tissues, which become black and malodorous. It is caused by infection or ischemia, such as from thrombosis . It is usually the result of critically insufficient blood supply and is often associated with diabetes and long-term smoking. This condition is most common in the lower extremities. The best treatment for gangrene is revascularization of the affected organ, which can reverse some of the effects of necrosis and allow healing. Other treatments include auto-amputation, debridement and local care, or surgical amputation. The method of treatment is generally determined depending on location of affected tissue and extent of tissue loss. (From the Wikpedia article Gangrene.)

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Recent Publications on Gangrene:
Hypernatremic Dehydration Leading to Peripheral Gangrene. Vectors based on herpes simplex virus type-1 (HSV-1) permit delivery of...	5th July, 2008	Department of Pediatrics, S.N. Children Hospital and MLN Medical College,	Indian Pediatr. 2008 Jun 7;45(6):513-514.
A case report of an effective treatment for diabetic foot ulcers with integration of traditional Chinese medicine and Western medicine. Diabetes contributes 75-85% of the factors predisposing to foot...	5th July, 2008	Department of Nephrology, West China Hospital of Sichuan University,	J Diabetes Complications. 2008 Jul 2;. DOI Direct Link
Long-term outcome of percutaneous transluminal angioplasty in chronic haemodialysis patients with peripheral arterial disease. BACKGROUND: Chronic haemodialysis patients are at an increased risk of...	4th July, 2008	1Department of Cardiovascular Surgery.	Nephrol Dial Transplant. 2008 Jul 2;. DOI Direct Link
COMPLICATIONS OF JOINT, TENDON, AND MUSCLE INJECTIONS. Prevention of complications is one of the most important aspects of...	2nd July, 2008	Department of Pain Management, Division of Anesthesiology, Critical Care,	Tech Reg Anesth Pain Manag. 2007 Jul;11(3):141-147. DOI Direct Link
[Fournier gangrene: presentation of 6 cases with no mortality.] INTRODUCTION: Fournier's gangrene is a serious and potentially lethal rare...	2nd July, 2008	Servicio de Cirugia General y del Aparato Digestivo. Hospital General	Cir Esp. 2008 Jul;84(1):28-31.
→View more research publications.

Gangrene Clinical Trials:
Stem Cell Study for Patients With Leg Ulcer/Gangrene	Leg Pain;   Ulcer;   Gangrene;   Ischemia;   Peripheral Vascular Diseases
Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-Threatening Ischemia	Peripheral Vascular Disease;   Diabetic Foot;   Peripheral Arterial Occlusive Disease;   Leg Ulcer;   Gangrene;   Ischemia
ACPs in Severe PAD/CLI by Direct Intramuscular Injection	Peripheral Arterial Disease;   Critical Limb Ischemia
Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections	Fasciitis, Necrotizing;   Severe Necrotizing Skin and Soft Tissue Infections;   Fournier's Gangrene
Intra-Arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI)	Peripheral Vascular Diseases;   Arterial Occlusive Diseases;   Leg Ulcer;   Gangrene;   Ischemia
→View more trials.

Gangrene Patents:
US Patent No.	Title
7332305	Genetic polymorphism in the Zf9 gene linked to inappropriate scarring or fibrosis
7351687	Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof
7351844	Bipolar trans carotenoid salts and their uses
7354575	Method and pharmaceutical composition for treating inflammation
7355035	Catalytic molecules
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Companies working in the area of Gangrene from Bioportfolio's Biocorporate database :
Company Name
LifeWave Ltd Incorporated in 2000, LifeWave Ltd. is a premier provider of innovative medical device in the field of Advanced Wound Management. The Company has developed an extensively researched and clinically... www.life-wave.com/        View full profile

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