Gastrectomy

A gastrectomy is a partial or full surgical removal of the stomach. The first successful gastrectomy was performed by Theodor Billroth in 1881 for cancer of the stomach. Gastrectomies are performed to treat cancer, severe cases of peptic ulcer disease, and perforations of the stomach wall. This procedure is becoming less common as peptic ulcers are now often treated with antibiotics for Helicobacter pylori or by endoscopy. In severe duodenal ulcers it may be necessary to remove the lower portion of the stomach called the pylorus and the upper portion of the small intestine called the duodenum. If there is a sufficient portion of the upper duodenum remaining a Billroth I procedure is performed, where the remaining portion of the stomach is reattached to the duodenum before the bile duct and the duct of the pancreas. If the stomach cannot be reattached to the duodenum a Billroth II is performed, where the remaining portion of the duodenum is sealed off, a hole is cut into the next section of the small intestine called the jejunum and the stomach is reattached at this hole. As the pylorus is used to grind food and slowly release the food into the small intestine, removal of the pylorus can cause food to move into the small intestine faster than normal, leading to gastric dumping syndrome.In the past a gastrectomy for peptic ulcer disease was often accompanied by a vagotomy, where the vagus nerve is cut to reduce acid production in the stomach. Nowadays, this problem is managed with proton pump inhibitors. (From the Wikpedia article Gastrectomy.)

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Recent Publications on Gastrectomy:
Laparoscopic subtotal gastrectomy for gastric carcinoma treatment. Laparoscopic surgery of the stomach is not well accepted in patients with...	11th July, 2008	University Department of Surgery, Clinical Hospital and Medical School	Hepatogastroenterology. 2008 Mar-Apr;55(82-83):814-6.
Effect of perioperative parenteral nutritional support for gastric cancer patients undergoing gastrectomy. BACKGROUND/AIMS: Malnutrition is frequently seen in gastric cancer...	11th July, 2008	Department of Surgery and Traumatology, National Taiwan University	Hepatogastroenterology. 2008 Mar-Apr;55(82-83):799-802.
Effects of mosapride citrate on patients after vagal nerve, lower esophageal sphincter, and pyloric sphincter-preserving nearly total gastrectomy reconstructed by jejunal J pouch interposition, and postoperative quality of life. BACKGROUND/AIMS: Vagal nerve and pylorus-preserving nearly total...	11th July, 2008	Department of Surgery, Nippon Dental University School of Life Dentistry	Hepatogastroenterology. 2008 Mar-Apr;55(82-83):760-5.
Efficacy of prophylactic extended lymphadenectomy with gastrectomy for patients with node-negative advanced gastric carcinoma. BACKGROUND/AIMS: Extended lymphadenectomy with gastrectomy is widely...	11th July, 2008	Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto,	Hepatogastroenterology. 2008 Mar-Apr;55(82-83):755-9.
Surgical treatment for gastric GIST with special reference to liver metastases. BACKGROUND/AIMS: Gastrointestinal stromal tumor (GIST) is recently defined...	11th July, 2008	Department of Surgery 1, Miyazaki University School of Medicine, 5200	Hepatogastroenterology. 2008 Mar-Apr;55(82-83):512-6.
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BioNews Results for Gastrectomy:
Gastrectomy - Research results from B.M. Quesada and co-authors update knowledge of gastrectomy	NewsRX:  Jun 25 2008 3:27PM Matching: gastrectomy

Gastrectomy Clinical Trials:
Evaluation of Four Reconstructions After Total Gastrectomy	Gastric Cancer;   Nutrition
Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery	Stomach Neoplasms;   Esophageal Neoplasms
Surgical Treatment of Type 2 Diabetes in Non-Morbidly Obese Patients	Diabetes Intervention: Procedure: Surgical Treatment
Advanced Medical Therapy vs. Advanced Medical Therapy Plus Bariatric Surgery for the Resolution of Type 2 Diabetes	Diabetes Mellitus, Type 2;   Obesity
Intraoperative Cell Saver Autotransfusion Use for Major Surgical Oncology Operations.	Pancreaticoduodenectomy;   Pancreatectomy;   Esophagectomy;   Gastrectomy;   Hepatectomy
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Gastrectomy Patents:
US Patent No.	Title
6861399	Cleaning compositions containing human serine protease T
6989363	Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
6991813	Physiological tissue repair and functional organ regeneration by cultivation of regenerative stem cells in vivo and in situ
7026285	Immunomodulating polymers
7030231	Membrane type serine protease 1 (MT-SP1) and uses thereof
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