Recent Publications on Hct116 Cells: |  |
Hsp90 Inhibition Abrogates the Topoisomerase I Poison-induced G2/M Checkpoint in p53-null Tumor cells by Depleting Chk1 and Wee1.
The G2/M cell cycle checkpoint is regulated by a multitude of signaling...
Direct Link | 30th September, 2008
| Memorial Sloan-Kettering Cancer Center.
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Cooperative effect of p21(Cip1/WAF-1) and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14(ARF).
P14(ARF) (p19(ARF) in the mouse) plays a central role in the regulation of...
Direct Link | 23rd September, 2008
| [1] 1Department of Hematology, Oncology and Tumor Immunology, University
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| [Effects of phosphatase of regenerating liver cell-3 gene silence by RNA interference on the expression of matrix metalloproteinases-2,-9 in human colon cancer cells.]
| 23rd September, 2008
| ancer Institute, Affiliated People's Hospital, Jiangsu University, Jiangsu
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Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.
BACKGROUND: Candidaspongiolide (CAN), a novel polyketide from a marine...
Direct Link | 19th September, 2008
| Tumor Hypoxia Laboratory, SAIC-Frederick, Inc., National Cancer Institute,
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| Resistance of colorectal cancer cells to 5-FUdR and 5-FU caused by Mycoplasma infection.
| 17th September, 2008
| Ottawa Health Research Institute, Centre for Cancer Therapeutics, Ottawa,
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Stress-induced down-regulation of tumor-associated NADH oxidase during apoptosis in transformed cells.
Tumor-associated NADH oxidase (tNOX) is a growth-related protein expressed...
Direct Link | 16th September, 2008
| Institute of Biomedical Sciences, National Chung Hsing University,
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| Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.
| 13th September, 2008
| Division of Anti-tumor Pharmacology, State Key Laboratory of Drug
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| SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression.
| 11th September, 2008
| Molecular Radiation Oncology, Center for Cancer Research, Radiation
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Characterization of TRIM31, upregulated in gastric adenocarcinoma, as a novel RBCC protein.
To explore the molecules associated with gastric adenocarcinoma, we used...
Direct Link | 6th September, 2008
| Discovery Research Laboratory, Tokyo R&D Center, Daiichi Pharmaceutical
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Expression of beta-F1-ATPase and mitochondrial transcription factor A and the change in mitochondrial DNA content in colorectal cancer: clinical data analysis and evidence from an in vitro study.
PURPOSE: Mitochondria play an important role in regulating apoptosis and...
Direct Link | 5th September, 2008
| Department of Clinical Pathology, Yang-Ming Campus, Taipei City Hospital,
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| HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling.
| 5th September, 2008
| Department of Molecular & Cell Biology, University of Connecticut, Storrs,
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Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells.
Celecoxib, a clinical non-steroidal anti-inflammatory drug, displays...
Direct Link | 2nd September, 2008
| Department of Biological Science and Technology, National Chiao Tung
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Increased Gene Targeting in Ku70 and Xrcc4 Transiently Deficient Human Somatic Cells.
The insertion of foreign DNA at a specific genomic locus directed by...
Direct Link | 2nd September, 2008
| Department of Animal Science, University of California, Davis, CA, USA.
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Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells.
Because of unsatisfactory treatment options for colon cancer, there is a...
Direct Link | 30th August, 2008
| Department of Dermatology, University of Wisconsin, Madison, Wisconsin.
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Cooperative exonization of MaLR and AluJo elements contributed an alternative promoter and novel splice variants of RNF19.
The RNF19 protein, which contains RING-finger and IBR motifs, acts as an...
Direct Link | 30th August, 2008
| Division of Biological Sciences, College of Natural Sciences, Pusan
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