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Hemangioma

A hemangioma is an abnormal build up of blood vessels in the skin or internal organs. It is also described as a congenital benign skin lesion consisting of dense, usually elevated masses of dilated blood vessels". In most cases, hemangiomas will disappear over time. They are formed either during gestation or appear during the first few weeks of life and may present as a birthmark. Hemangiomas are the most common childhood tumor occurring in approximately ten percent of Caucasians, and are less prevalent in other races. Females are three to five times more likely to have hemangiomas than males. Hemangiomas can be vivid superficial lesions, known as capillary hemangiomas , or they can be deep bluish swelling, known as cavernous hemangiomas. Sometimes they can be both superficial and deep. Approximately eighty percent are located on the face and neck, with the next most prevalent location being the liver. Although hemangiomas are benign, some serious complications can occur. The cause of hemangioma is currently unknown; however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation. In 2007, a paper from the Stanford Children's Surgical Laboratory revealed that localized soft tissue hypoxia coupled with increased circulating estrogen after birth may be the stimulus. There is also a hypothesis presented by researchers at Harvard and the University of Arkansas that maternal placenta embolizes to the fetal dermis during gestation resulting in hemangiomagenesis, yet Duke researchers conducted genetic analyses of small nucleotide polymorphisms in hemangioma tissue compared to the mother's DNA that contradicted this notion. More research is required in order to fully understand the explosive nature of hemangioma growth which will hopefully yield targeted therapeutics to treat its most complicated presentations. (From the Wikpedia article Hemangioma.)

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Recent Publications on Hemangioma:

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[Ultrasonography in differential diagnosis of focal liver neoplasms.]
Results of diagnosis and treatment of 2576 patients with focal lesions of...
4th October, 2008
Klinika obshchei khirurgii i usovershenstvovaniia po endoskopicheskoi Khirurgiia (Mosk). 2008;(7):48-53.
OCT and ultrasound biomicroscopic findings in iris arteriovenous malformation.
Iris arteriovenous malformation, also labeled as iris racemose hemangioma,...
4th October, 2008
Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA. Ophthalmic Surg Lasers Imaging. 2008 Sep-Oct;39(5):426-8.
Receiver operating characteristic analysis of diffusion-weighted magnetic resonance imaging in differentiating hepatic hemangioma from other hypervascular liver lesions.
PURPOSE: To evaluate the role of diffusion-weighted imaging in...
3rd October, 2008
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns J Comput Assist Tomogr. 2008 Sep-Oct;32(5):750-6.
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Lumbar epidural capillary hemangioma presenting as lumbar disc herniation disease: case report.
STUDY DESIGN: A case of lumbar spinal epidural hemangioma is presented....
2nd October, 2008
Department of Neurosurgery, GATA Haydarpasa Training Hospital, Istanbul, Spine. 2008 Oct 1;33(21):E795-7.
DOI Direct Link
Huge cardiac hemangioma.
STUDY DESIGN: A case of lumbar spinal epidural hemangioma is presented....
1st October, 2008
Division of Cardiology, Department of Internal Medicine, Hallym University Eur J Cardiothorac Surg. 2008 Sep 27.
DOI Direct Link

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BioNews Results for Hemangioma:

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Nitrosated Derivatives Of 2,5-dihydroxybenzene Compounds
Therapeutics Daily:  Sep 29 2008 4:23PM Matching: hemangioma
Central Serous Retinopathy
Retinal Physician:  Sep 22 2008 2:04PM Matching: hemangioma
Woman complains of transient decreased vision in left eye
OSN Super Site:  Sep 11 2008 3:07AM Matching: hemangioma
Massive Hemorrhage in Pregnancy Caused by a Diffuse Cavernous Hemangioma of the Rectum -- EUS as Imaging Modal
General Medicine eJournal:  Sep 3 2008 1:49PM Matching: hemangioma

Hemangioma Clinical Trials:

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Propranolol in Capillary Hemangiomas
Hemangioma, Capillary

Hemangioma Patents:

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US Patent No.Title
7378386 Anti-viral treatment methods using phosphatidylethanolamine-binding peptide derivatives
7393829 Pharmaceutical compositions comprising fragments and homologs of troponin subunits
7393833 Chimeric proteins with phosphatidylserine binding domains
7393837 Inhibition of PEX in the treatment of metabolic bone diseases
7393870 3-(heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors

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BioPortfolio Ltd. offers e-mail and postal lists for Hemangioma scientists - we have details of around 2173 individuals working on Hemangioma .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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