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Hemangioma

A hemangioma is an abnormal build up of blood vessels in the skin or internal organs. It is also described as a congenital benign skin lesion consisting of dense, usually elevated masses of dilated blood vessels". In most cases, hemangiomas will disappear over time. They are formed either during gestation or appear during the first few weeks of life and may present as a birthmark. Hemangiomas are the most common childhood tumor occurring in approximately ten percent of Caucasians, and are less prevalent in other races. Females are three to five times more likely to have hemangiomas than males. Hemangiomas can be vivid superficial lesions, known as capillary hemangiomas , or they can be deep bluish swelling, known as cavernous hemangiomas. Sometimes they can be both superficial and deep. Approximately eighty percent are located on the face and neck, with the next most prevalent location being the liver. Although hemangiomas are benign, some serious complications can occur. The cause of hemangioma is currently unknown; however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation. In 2007, a paper from the Stanford Children's Surgical Laboratory revealed that localized soft tissue hypoxia coupled with increased circulating estrogen after birth may be the stimulus. There is also a hypothesis presented by researchers at Harvard and the University of Arkansas that maternal placenta embolizes to the fetal dermis during gestation resulting in hemangiomagenesis, yet Duke researchers conducted genetic analyses of small nucleotide polymorphisms in hemangioma tissue compared to the mother's DNA that contradicted this notion. More research is required in order to fully understand the explosive nature of hemangioma growth which will hopefully yield targeted therapeutics to treat its most complicated presentations. (From the Wikpedia article Hemangioma.)

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Recent Publications on Hemangioma:

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Hematoma in the cervical ligamentum flavum. Report of a case and review of the literature.
Hematoma of the cervical ligamentum flavum is very rare, and its...
31st October, 2009
Department of Orthopedics, Institute of Health Biosciences, The University Skeletal Radiol. 2009 Oct 30.
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Cavernous hemangioma: a rare cause for secondary parkinsonism: a case report.
A 72-year-old female was admitted to our outpatient clinic with the...
30th October, 2009
Faculty of Medicine, Department of Neurology, Kafkas University, Kars, Int J Neurosci. 2009;119(11):2112-7.
A rare vascular tumor of the external auditory canal: the capillary hemangioma.
A 32-year-old woman presented to our department with a 10-month history of...
29th October, 2009
Department of Otolaryngology, Vakif Gureba Training and Research Hospital, Kulak Burun Bogaz Ihtis Derg. 2009 Jul-Aug;19(4):212-5.
Psychosocial Adjustment in Children and Adolescents with a Craniofacial Anomaly: Diagnosis-Specific Patterns.
Objective: To obtain descriptive information about diagnosis-specific...
29th October, 2009
Cleft Palate Craniofac J. 2009 Oct 13:1.
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[Propranolol therapy to treat problematic hemangiomas : A new standard therapy makes its debut.]
Small hemangiomas sometimes produce large findings. Depending on...
28th October, 2009
Hautklinik, SLS-Kliniken GmbH, Am Gesundbrunnen 20-26, 74078, Heilbronn, Hautarzt. 2009 Oct 25.
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BioNews Results for Hemangioma:

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High Dose Iodine 125 Episcleral Brachytherapy for Circumscribed Choroidal Hemangioma.
British Journal of Ophthalmology:  Oct 14 2009 11:26PM Matching: hemangioma
High Dose Iodine 125 Episcleral Brachytherapy for Circumscribed Choroidal Hemangioma. [Clinical Science]
British Journal of Ophthalmology:  Oct 13 2009 4:09AM Matching: hemangioma
Round table: Vision screenings vs. mandatory exams, MRI vs. CT
PCON SuperSite:  Oct 13 2009 12:49PM Matching: hemangioma
Experts To Examine New Treatment Options For Vascular Anomalies
Medical News Today:  Oct 9 2009 9:47AM Matching: hemangioma
Ohio Infants Undergo Facial Surgery In New York
WCBS-TV:  Oct 2 2009 8:39PM Matching: hemangioma
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Hemangioma Clinical Trials:

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Propranolol in Capillary Hemangiomas

Hemangioma Patents:

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US Patent No.Title
7572794 Anthranilamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors
7579473 c-Met modulators and methods of use
7582441 Methods and compositions for treating and diagnosing disease
7582662 Body weight gain inhibitor
7582668 Imidazoyl-benzamide anti-cancer agents

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BioPortfolio Ltd. offers e-mail and postal lists for Hemangioma scientists - we have details of around 2173 individuals working on Hemangioma .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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