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Hemoperfusion

Hemoperfusion is a medical process used to remove toxic substances from a patients blood. The technique involves passing large volumes of blood over an adsorbent substance. The adsorbent substance most commonly used in hemoperfusion are resins and activated carbon. Hemoperfusion is an extracorporeal form of treatment because the blood is pumped through a device outside the patient's body. Its major uses include removing drugs or poisons from the blood in emergency situations, removing waste products from the blood in patients with renal failure, and as a supportive treatment for patients before and after liver transplantation. (From the Wikpedia article Hemoperfusion.)

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Recent Publications on Hemoperfusion:

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Polymyxin B hemoperfusion and mortality in abdominal septic shock.
BACKGROUND AND OBJECTIVES: Diarrhea-associated hemolytic uremic syndrome...
12th November, 2009
JAMA. 2009 Nov 11;302(18):1969.
DOI Direct Link
Polymyxin B hemoperfusion and mortality in abdominal septic shock.
BACKGROUND AND OBJECTIVES: Diarrhea-associated hemolytic uremic syndrome...
12th November, 2009
JAMA. 2009 Nov 11;302(18):1968.
DOI Direct Link
Polymyxin B hemoperfusion and mortality in abdominal septic shock.
BACKGROUND AND OBJECTIVES: Diarrhea-associated hemolytic uremic syndrome...
12th November, 2009
JAMA. 2009 Nov 11;302(18):1968-9.
DOI Direct Link
Hemoperfusion with polymyxin B-immobilized fiber column improves liver function after ischemia-reperfusion injury.
AIM: To investigate the usefulness of direct hemoperfusion with a...
5th November, 2009
Department of Thoracic and Visceral Organ Surgery, Gunma University World J Gastroenterol. 2009 Sep 28;15(36):4571-5.
Effect of charcoal hemoperfusion for removal of plasma methotrexate in a patient with acute renal failure.
Strategies effective for accelerating methotrexate removal in delayed...
30th October, 2009
Department of Homeostatic Regulation and Development, Niigata University Pediatr Hematol Oncol. 2009 Oct-Nov;26(7):520-5.

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Press Releases About Hemoperfusion:

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Spectral announces publication demonstrating Toraymyxin(TM) significantly reduces mortality from sepsis in prospective controlled trial 18th June, 2009 Spectral Diagnostics Inc.
TORONTO, June 18 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI), a company developing products for the treatment of sepsis, today announced that findings demonstrating the Toraymyxin(TM)

BioNews Results for Hemoperfusion:

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Polymyxin B Hemoperfusion and Mortality in Abdominal Septic Shock
Journal of the American Medical Association:  Nov 10 2009 10:52PM Matching: hemoperfusion
Polymyxin B Hemoperfusion and Mortality in Abdominal Septic ShockReply
Journal of the American Medical Association:  Nov 10 2009 10:52PM Matching: hemoperfusion
A Longer Duration of Polymyxin B-Immobilized Fiber Column Hemoperfusion Improves Pulmonary Oxygenation in Patients With Septic Shock
MDLinx:  Oct 20 2009 10:52AM Matching: hemoperfusion

Hemoperfusion Clinical Trials:

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Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis

Hemoperfusion Patents:

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US Patent No.Title
7141716 Inbred miniature swine and uses thereof
7341843 Botulinum toxin A peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy
7342083 Polyamine polymers
7348176 Chamber with adjustable volume for cell culture and organ assist
7374791 Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser

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Companies working in the area of Hemoperfusion from Bioportfolio's Biocorporate database :

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Company Name

MedaSorb Technologies

MedaSorb Technologies (“MedaSorb” or the “Company) has developed a new platform technology that efficiently removes toxic compounds from the bloodstream. Current state-of-the-art blood purification...
www.medasorb.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Hemoperfusion scientists - we have details of around 329 individuals working on Hemoperfusion .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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