Herpangina

Herpangina from herp, an itching, and angina, a sore throat, literally "a choking"; also called mouth blisters) is the name of a painful mouth infection caused by coxsackieviruses. Usually, herpangina is produced by one particular strain of coxsackievirus A, but it can also be caused by coxsackievirus B or echoviruses. It is most common in children. Though herpangina can be asymptomatic, symptoms usually associated are high fever and sore throat.A small number of lesions form in the back area of the mouth, particularly the soft palate or tonsillar pillars. The lesions progress initially from red macules to vesicles and lastly to ulcerations which can be 2 - 4 mm in size. The lesions heal in 7 - 10 days.Histologically, the epithelial cells show signs of intracelular and intercellular edema. A diagnosis can be made from clinical signs and symptoms, and treatment consists of minimizing the discomfort of symptoms. Aspirin is avoided. (From the Wikpedia article Herpangina.)

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Recent Publications on Herpangina:
Enterovirus 71: epidemiology, pathogenesis and management. Enterovirus 71 (EV71) has emerged as a major cause of neurological threat...	27th October, 2009	Department of Emergency Medicine, College of Medicine, National Cheng Kung	Expert Rev Anti Infect Ther. 2009 Aug;7(6):735-42. DOI Direct Link
[Therapeutic effect of ribavirin aerosol on herpangina in children] Background and Aims Hand-foot-and-mouth disease (HFMD) and herpangina are...	26th August, 2009	Department of Pediatrics, Zhuji People's Hospital, Zhuji, Zhejiang 311800,	Zhongguo Dang Dai Er Ke Za Zhi. 2009 Jun;11(6):494-5.
Study on Risk Factors for Severe Hand-foot-and-mouth Disease. Background and Aims Hand-foot-and-mouth disease (HFMD) and herpangina are...	12th August, 2009	Field Epidemiology Training Program, Infectious Disease Surveillance	Pediatr Int. 2009 Aug 3. DOI Direct Link
Prevalence of enterovirus from patients with herpangina and hand, foot and mouth disease in Nagano Prefecture, Japan, 2007. Background and Aims Hand-foot-and-mouth disease (HFMD) and herpangina are...	8th October, 2008	Public Health Division, Nagano Environmental Conservation Research	Jpn J Infect Dis. 2008 May;61(3):247-8.
Enterovirus detection status of patients with herpangina and hand, foot and mouth disease in epidemic season 2007, Kanagawa Prefecture, Japan. Hand, foot and mouth disease (HFMD) is a viral infection of children...	19th September, 2008	Department of Biology, Kanagawa Prefectural Institute of Public Health,	Jpn J Infect Dis. 2008 Mar;61(2):162-3.
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Herpangina Patents:
US Patent No.	Title
7579465	Antiviral agents
6630335	14171 protein kinase, a novel human protein kinase and uses thereof
6458577	Methods of culturing and assaying a virus in a specimen and compositions and cell lines for doing the same
6458346	Broad spectrum microbicidal and spermicidal compositions, devices, and methods
5411733	Antiviral agent containing crude drug
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BioPortfolio Ltd. offers e-mail and postal lists for Herpangina scientists - we have details of around 18 individuals working on Herpangina .