Histocompatibility

Histocompatibility is the property of having the same, or mostly the same, alleles of a set of genes called the major histocompatibility complex. These genes are expressed in most tissues as antigens, to which the immune system makes antibodies. The immune system at first makes antibodies to all sorts of antigens, including those it has never been exposed to, but stops making them to antigens present in the body. If the body is exposed to foreign antigens, as by getting a tissue graft, it attacks the foreign material unless it is histocompatible.A similar system exists in many plants; its purpose is not to reject grafts, but to prevent inbreeding. Pollen from a plant sharing a histocompatibility gene with the female either fails to grow or dies soon after germinating. (From the Wikpedia article Histocompatibility.)

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Recent Publications on Histocompatibility:
Split immunological tolerance to trophoblast. Split immunological tolerance refers to states in which an individual is...	31st October, 2009	Department of Veterinary Basic Sciences, The Royal Veterinary College,	Int J Dev Biol. 2009 Oct 16. DOI Direct Link
On the role of placental Major Histocompatibility Complex and decidual leukocytes in implantation and pregnancy success using non-human primate models. While there is broad agreement that interactions of the human maternal...	31st October, 2009	Department of Comparative Biosciences, School of Veterinary Medicine,	Int J Dev Biol. 2009 Oct 2. DOI Direct Link
IPD--the Immuno Polymorphism Database. The Immuno Polymorphism Database (IPD) (http://www.ebi.ac.uk/ipd/) is a...	31st October, 2009	Anthony Nolan Research Institute, Royal Free Hospital, Pond Street,	Nucleic Acids Res. 2009 Oct 29. DOI Direct Link
No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis. Abstract We determined the alleles of KIR3DL1 and KIR3DS1 in a cohort of...	31st October, 2009	Northern Ireland Regional Histocompatibility and Immunogenetics	Tissue Antigens. 2009 Oct 28. DOI Direct Link
TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo. Cross-presentation of soluble protein antigens on major histocompatibility...	31st October, 2009	Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, 171 77	Scand J Immunol. 2009 Nov;70(5):431-8. DOI Direct Link
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Press Releases About Histocompatibility:
deCODE-led Megastudy Finds New Genetic Clues to Causes of Schizophrenia	1st July, 2009	DeCODE Genetics Inc	REYKJAVIK, Iceland, July 1 /PRNewswire-FirstCall/ -- The largest study of the genetics of schizophrenia ever undertaken has revealed several new common single-letter variants in the sequence of
Vical Signs Binding Letter of Intent for Sales and Marketing of Allovectin-7(R) in Turkey	3rd December, 2008	Vical Incorporated	SAN DIEGO, Dec. 3 /PRNewswire-FirstCall/ -- Vical Incorporated (Nasdaq: VICL) today announced an exclusive, binding letter of intent with EIP Eczacibasi Ilac Pazarlama A.S. (EIP) for sales and
Oxford University researchers and local company work together to	1st June, 2005	Proimmune	Oxford University researchers and local company work together to accelerate HIV vaccine research Oxford, UK, 15 June 2005 …. Scientists in Oxford, developing a vaccine for HIV, hope to

BioNews Results for Histocompatibility:
American Society for Histocompatibility and Immunogenetics Hosts 2009 Annual Meeting Nov. 2-6	BioSpace:  Oct 8 2009 8:48PM Matching: histocompatibility
Research and Markets: Immunology: Understanding The Immune System, 2nd Edition	RBC Dain Rauscher:  Sep 21 2009 12:57PM Matching: histocompatibility
Vical and Teva Establish Sales and Marketing Agreement for Allovectin-7(r) in Israel	Stockwatch:  Aug 3 2009 10:37AM Matching: histocompatibility

Histocompatibility Clinical Trials:
Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies

Histocompatibility Patents:
US Patent No.	Title
7598093	Nanoparticle and microparticle based detection of cellular products
7601531	Chlamydia pneumoniae polynucleotides and uses thereof
7601697	Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
7601699	Production of reprogrammed cells with restored potential
7601801	HLA-A24 binding cancer antigen peptide derived from livin
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Companies working in the area of Histocompatibility from Bioportfolio's Biocorporate database :
Company Name
Forensic Analytical Molecular Genetics Division Comprised of leading research scientists from the field of HLA typing, Forensic Analytical's Molecular Genetics Division offers a variety of products and services that address the needs of immu... www.forensica.com/        View full profile
Altor BioScience Corporation Altor BioScience Corporation is a biopharmaceutical company developing a new class of therapeutic products for the treatment of cancer, viral infections and autoimmune diseases. Altor’s drug discovery... www.sunolmolecular.com/        View full profile

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