Hyperinsulinism

Hyperinsulinism or hyperinsulinemia refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and blood levels are closely related to the level of glucose in the blood, so that a given level of insulin can be normal for one blood glucose level but low or high for another. Hyperinsulinism can be associated with several types of medical problems, which can be roughly divided into two broad categories: those tending toward reduced sensitivity to insulin and high blood glucose levels , and those tending toward excessive insulin secretion and low glucose levels . (From the Wikpedia article Hyperinsulinism.)

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Recent Publications on Hyperinsulinism:
Metabolic Syndrome Racial Differences in Adolescents. The metabolic syndrome consists of obesity, insulin resistance,...	21st November, 2009	Division of Pediatric Endocrinology, Department of Pediatrics, The Ohio	Curr Diabetes Rev. 2009 Nov;5(4):259-265.
Hyperinsulinemia is a predictor of new cardiovascular events in Colombian patients with a first myocardial infarction. BACKGROUND: Acute Myocardial Infarction (AMI) is one of the main causes of...	20th November, 2009	VILANO Group and Cardiology Group. Research Institute, Fundacion	Int J Cardiol. 2009 Nov 16. DOI Direct Link
Limited Value of 18F-F-DOPA PET to Localize Pancreatic Insulin-Secreting Tumors in Adults with Hyperinsulinemic Hypoglycemia. Context: Fluorine-18-L-dihydroxyphenylalanine positron emission tomography...	17th November, 2009	Service Central de Biophysique et de Medecine Nucleaire (L.T., D.T.,	J Clin Endocrinol Metab. 2009 Nov 13. DOI Direct Link
Could insulin sensitization be used as an alternative to intensive insulin therapy to improve the survival of intensive care unit patients with stress-induced hyperglycemia? Glucokinase is essential for glucose-stimulated insulin release from the...	17th November, 2009		Crit Care Med. 2009 Oct;37(10):2856-8. DOI Direct Link
Time-dependent regulation of muscle caveolin activation and insulin signalling in response to high-fat diet. We studied the effect of high-fat diet on the expression and activation of...	17th November, 2009	Department of Biochemistry and Molecular Biology, University of Navarra,	FEBS Lett. 2009 Oct 6;583(19):3259-64. Epub 2009 Sep 12. DOI Direct Link
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Press Releases About Hyperinsulinism:
Treatment Corrects Severe Insulin Imbalance in Animal Studies	31st July, 2008	The Children's Hospital of Philadelphia	--Could Become First Effective Drug for Rare Genetic Disorder in Children-- PHILADELPHIA, July 31 /PRNewswire-USNewswire/ -- Researchers have used a drug to achieve normal levels of blood sugar in

Hyperinsulinism Patents:
US Patent No.	Title
7115372	Methods for targeting RNA molecules
7276352	Induction of .beta. cell differentiation in human cells by stimulation of the GLP-1 receptor
7300927	Method for treating or preventing Alzheimer's disease
7304063	Inhibitors of Akt activity
7312304	Somatostatin agonists
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Companies working in the area of Hyperinsulinism from Bioportfolio's Biocorporate database :
Company Name
Ambry Genetics Ambry Genetics provides answers to clinicians, patients, and researchers with comprehensive, reliable, and state-of-the-art DNA diagnostic testing. The Company is well known for its Cystic Fibrosis... www.ambrygen.com/        View full profile

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