Hyperinsulinism

Hyperinsulinism or hyperinsulinemia refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and blood levels are closely related to the level of glucose in the blood, so that a given level of insulin can be normal for one blood glucose level but low or high for another. Hyperinsulinism can be associated with several types of medical problems, which can be roughly divided into two broad categories: those tending toward reduced sensitivity to insulin and high blood glucose levels , and those tending toward excessive insulin secretion and low glucose levels . (From the Wikpedia article Hyperinsulinism.)

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Recent Publications on Hyperinsulinism:
[Obesity and polycystic ovary syndrome: reproductive issues] Polycystic ovary syndrome (PCOS) is responsible for most cases of...	26th November, 2008	Service de Gynecologie endocrinienne et Medecine de la Reproduction,	Bull Acad Natl Med. 2008 Apr;192(4):649-59; discussion 659-60.
Polycystic ovary syndrome: treatment strategies and management. BACKGROUND: The polycystic ovary syndrome (PCOS) is possibly the most...	19th November, 2008	University of Alcala, Hospital Universitario Ramon y Cajal, Centro de	Expert Opin Pharmacother. 2008 Dec;9(17):2995-3008.
Predictive value of postoperative glycosuria after partial elective pancreatectomy in focal congenital hyperinsulinism. BACKGROUND: High-glycemic-load diets may increase colorectal cancer risk...	19th November, 2008		Diabetes Care. 2008 Oct;31(10):e71. DOI Direct Link
Identification of Mutations in the Kir6.2 Subunit of the K(ATP) Channel. The beta-cell ATP-sensitive potassium channel is a key component of...	11th November, 2008	Institute of Biomedical and Clinical Science, Peninsula Medical School,	Methods Mol Biol. 2009;491:235-45. DOI Direct Link
Noninsulinoma pancreatogenous hypoglycemia syndrome in a Saudi male. Nesidioblastosis is focal or diffuse islet hyperplasia leading to...	11th November, 2008	Department of Medicine, King Khalid National Guard Hospital, PO Box 9515,	Saudi Med J. 2008 Nov;29(11):1654-7.
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Hyperinsulinism Clinical Trials:
Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism	Congenital Hyperinsulinism;   Hyperinsulinism;   Persistent Hyperinsulinemic Hypoglycemia of Infancy;   CHI;   PHHI

Hyperinsulinism Patents:
US Patent No.	Title
6862466	Methods of monitoring glucose levels in a subject and uses thereof
7078186	Apoptosis related polynucleotides, polypeptides, and antibodies
7091247	Biphenyl compound
7094753	Somatostatin analog and uses thereof
7109166	Sustained release formulation of a peptide
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