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Hyperparathyroidism

Hyperparathyroidism is overactivity of the parathyroid glands resulting in excess production of parathyroid hormone . The parathyroid hormone regulates calcium and phosphate levels and helps to maintain these levels. Overactivity of one or more of the parathyroid glands causes high calcium levels and low levels of phosphate in the blood. Hyperparathyroidism was first described and treated in the 1930s by Fuller Albright of Massachusetts General Hospital, working at the Mallinckrodt General Clinical Research Center. The oldest known case was found in a cadaver from a Early Neolithic cemetery in southwest Germany. (From the Wikpedia article Hyperparathyroidism.)

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Recent Publications on Hyperparathyroidism:

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The tumor suppressor parafibromin is required for posttranscriptional processing of histone mRNA.
Parafibromin, encoded by the gene HRPT2, is a tumor suppressor protein...
13th November, 2009
Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Mol Carcinog. 2009 Nov 11.
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The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
Parafibromin, a component of the RNA polymerase II-associated PAF1...
13th November, 2009
College of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746 Nucleic Acids Res. 2009 Nov 11.
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Dosing-time dependent effect of dexamethasone on bone density in rats.
AIMS: While glucocorticoids are widely used to treat patients with various...
12th November, 2009
Division of Clinical Pharmacology, Department of Pharmacology, Jichi Life Sci. 2009 Nov 7.
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Surgical findings and post-operative parathormone levels in patients with secondary hyperparathyroidism.
OBJECTIVE: The peri-operative and immediate post-operative outcome of...
12th November, 2009
Department of Otorhinolaryngology, Head and Neck Surgery, University B-ENT. 2009;5(3):143-8.
Insulin resistance is not coupled with defective insulin secretion in primary hyperparathyroidism.
AIMS: An increased frequency of both impaired glucose tolerance and Type 2...
11th November, 2009
Division of Endocrinology and Metabolism, Santa Croce e Carle Hospital, Diabet Med. 2009 Oct;26(10):968-73.
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Press Releases About Hyperparathyroidism:

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DaVita Abstracts Accepted into American Society of Nephrology Meeting 4th November, 2008 DaVita Inc.
EL SEGUNDO, Calif., Nov. 4 /PRNewswire/ -- DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), in conjunction with DaVita Clinical
Cytochroma Announces Initiation of Phase II Clinical Trial Of CTA018 For Chronic Kidney Disease Patients 23rd October, 2008
MARKHAM, Canada, October 23 /PRNewswire/ -- Cytochroma today announced that it has initiated a Phase II clinical trial of CTA018 Injection, the Company's product candidate for the treatment of
Cytochroma and Mitsubishi Tanabe Form Partnership for Chronic Kidney Disease Therapies in U.S. and Asia 30th July, 2008
MARKHAM, Canada and OSAKA, Japan, July 30 /PRNewswire/ -- Cytochroma and Mitsubishi Tanabe Pharma Corporation ("MTPC") today announced that the companies have signed a license agreement
Cytochroma and Mitsubishi Tanabe form partnership for chronic kidney disease therapies in U.S. and Asia 30th July, 2008 Cytochroma
MARKHAM, ON, and OSAKA, Japan, July 30 /PRNewswire/ - Cytochroma and Mitsubishi Tanabe Pharma Corporation ("MTPC") today announced that the companies have signed a license agreement under

BioNews Results for Hyperparathyroidism:

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Secondary Hyperparathyroidism: Pathophysiology and Treatment
Medscape:  Nov 10 2009 11:53PM Matching: hyperparathyroidism
The Value of Intraoperative Parathyroid Hormone Monitoring in Localized Primary Hyperparathyroidism: A Cost Analysis
MDLinx:  Nov 9 2009 11:52AM Matching: hyperparathyroidism
Medical News: Invitation To Attend The World Congress On Osteoporosis 2010 (IOF WCO - ECCEO10)
Medical News Today:  Oct 28 2009 3:16PM Matching: hyperparathyroidism
Persistent Secondary Hyperparathyroidism and Vertebral Fractures in Kidney Transplantation: Role of Calcium-Sensing Receptor Polymorphisms and Vitamin D Deficiency
MDLinx:  Oct 28 2009 12:54PM Matching: hyperparathyroidism
Invitation To Attend The World Congress On Osteoporosis 2010 (IOF WCO - ECCEO10)
Medical News Today:  Oct 28 2009 12:28PM Matching: hyperparathyroidism
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Hyperparathyroidism Clinical Trials:

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Energy Specific Far Infrared Radiation Treatment for Hyperparathyroidism

Hyperparathyroidism Patents:

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US Patent No.Title
7524938 Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins
7550569 Antibodies that specifically bind to GMAD
7553828 9-aminomethyl substituted minocycline compounds
7553860 Substituted gamma lactams as therapeutic agents
7557135 Inhibitors of cytosolic phospholipase A.sub.2

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Companies working in the area of Hyperparathyroidism from Bioportfolio's Biocorporate database :

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Bone Care International Incorporated

Bone Care is a leader in the discovery and development of improved vitamin D-hormone therapies for the treatment of secondary hyperparathyroidism and certain hyperproliferative diseases. D-hormones...
www.bondeville.com/        View full profile
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NPS Pharmaceuticals

NPS Pharmaceuticals is engaged in the discovery, development and commercialization of therapeutic small molecules and recombinant proteins to treat bone and mineral, gastrointestinal and central...
www.npsp.com/        View full profile
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Sensipar® (cinacalcet HCl)

Sensipar® (cinacalcet HCl) is an innovative, first-in-class, oral therapy indicated to treat hyperparathyroidism (excessive levels of parathyroid hormone) caused by chronic kidney disease; it is...
www.sensipar.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Hyperparathyroidism scientists - we have details of around 1925 individuals working on Hyperparathyroidism .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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