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Hypoglycemia

Hypoglycemia is the medical term for a pathologic state produced by a lower than normal level of glucose in the blood. The term hypoglycemia literally means "under-sweet blood" . Hypoglycemia can produce a variety of symptoms and effects but the principal problems arise from an inadequate supply of glucose as fuel to the brain, resulting in impairment of function . Derangements of function can range from vaguely "feeling bad" to coma and permanent brain damage or death. Hypoglycemia can arise from many causes and can occur at any age. The most common forms of moderate and severe hypoglycemia occur as a complication of treatment of diabetes mellitus with insulin or certain oral medications. Hypoglycemia is usually treated by the ingestion or administration of dextrose, or foods digestible to glucose.Endocrinologists typically consider the following criteria as proving that an individual's symptoms can be attributed to hypoglycemia:#Symptoms known to be caused by hypoglycemia#Low glucose at the time the symptoms occur#Reversal or improvement of symptoms or problems when the glucose is restored to normalHowever, not everyone has accepted these suggested diagnostic criteria, and even the level of glucose low enough to define hypoglycemia has been a source of controversy in several contexts. For many purposes, plasma glucose levels below 70 mg/dl or 3.9 mmol/L are considered hypoglycemic; these issues are detailed below. (From the Wikpedia article Hypoglycemia.)

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Recent Publications on Hypoglycemia:

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Selective peroxisome proliferator-activated receptor {gamma} (PPAR{gamma}) modulation as a strategy for safer therapeutic PPAR{gamma} activation.
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a...
13th November, 2009
From InteKrin Therapeutics Inc, Los Altos, CA. Am J Clin Nutr. 2009 Nov 11.
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Continuous glucose monitor shows potential for early hypoglycemia detection in hospitalized patients.
OBJECTIVE: This study shows the potential of continuous glucose monitoring...
13th November, 2009
Department of Medicine, The Artificial Pancreas Center, Philadelphia, Diabetes Technol Ther. 2009 Nov;11(11):745-7.
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Rationale, design, and baseline data of the insulin glargine (Lantus) versus insulin detemir (Levemir) Treat-To-Target (L2T3) study: A multinational, randomized noninferiority trial of basal insulin initiation in type 2 diabetes.
OBJECTIVE: To discuss the design and baseline data of the Lantus...
13th November, 2009
Department of Internal Medicine, Academic Medical Center, Amsterdam, the Diabetes Technol Ther. 2009 Nov;11(11):739-43.
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Role of continuous subcutaneous insulin infusion in patients with recalcitrant diabetes in South India.
BACKGROUND: We aimed to assess the effect of continuous subcutaneous...
13th November, 2009
Dr. Mohan's Diabetes Specialities Centre & Madras Diabetes Research Diabetes Technol Ther. 2009 Nov;11(11):733-7.
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Improved quality of glycemic control and reduced glycemic variability with use of continuous glucose monitoring.
OBJECTIVE: We evaluated effects of unmasking of continuous display of...
13th November, 2009
Biomedical Informatics Consultants, Potomac, Maryland 20854-4721, USA. Diabetes Technol Ther. 2009 Nov;11(11):717-23.
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Press Releases About Hypoglycemia:

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Hypoglycemia Education - A Vital Weapon in the Battle to Conquer Diabetes 12th November, 2009 ESP Bioscience
LONDON, November 12 /PRNewswire/ -- The on-line journal Diabetic Hypoglycemia (http://www.hypodiab.com/) supports the message of World Diabetes Day 2009 (http://www.worlddiabetesday.org) in their
Blood Glucose Control Vital as Childhood Diabetes is set to Double 28th September, 2009
LONDON, September 28 /PRNewswire/ -- A recent Lancet article predicted a doubling of new cases of type 1 diabetes in European children aged under 5, and a 70% rise in cases in children under 15 years
Novo Nordisk Insulin Analogs Have Proven Safety Profiles 28th June, 2009 Novo Nordisk
PRINCETON, N.J., June 28 /PRNewswire/ -- On Friday June 26, Diabetologia, the journal of the European Association for the Study of Diabetes (EASD) published online data from four studies relating to
Novo Nordisk Warns Customers About Stolen Insulin 13th June, 2009 Novo Nordisk
PRINCETON, N.J., June 13 /PRNewswire-FirstCall/ -- Novo Nordisk product previously reported as stolen in North Carolina has resurfaced recently at a medical center in Houston. Three lots of 10 ml
Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride 8th June, 2009 Novo Nordisk
NEW ORLEANS, June 8 /PRNewswire-FirstCall/ -- Novo Nordisk (NVO) data presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) showed that once-daily liraglutide,

BioNews Results for Hypoglycemia:

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Recent Studies Suggest Benefits of Continuous Glucose Monitoring
Freshnews.com:  Nov 13 2009 5:23PM Matching: hypoglycemia
Recent Studies Suggest Benefits of Continuous Glucose Monitoring
Genetic Engineering News:  Nov 13 2009 3:30PM Matching: hypoglycemia
Novartis collaborates with International Diabetes Federation
Pharmacy Europe:  Nov 13 2009 11:35AM Matching: hypoglycemia
Education - a vital weapon in the battle to conquer diabetes
BioPortfolio:  Nov 12 2009 4:47PM Matching: hypoglycemia
Hypoglycemia Education - A Vital Weapon in the Battle to Conquer Diabetes
Montana's News Station:  Nov 12 2009 1:15PM Matching: hypoglycemia
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Hypoglycemia Clinical Trials:

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Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes

Hypoglycemia Patents:

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US Patent No.Title
7592010 Albumin fusion proteins
7598416 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
7599726 System and methods for processing analyte sensor data
7601688 Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
7601719 Compounds, methods and pharmaceutical compositions for inhibiting PARP

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Companies working in the area of Hypoglycemia from Bioportfolio's Biocorporate database :

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NiliMEDIX

NiliMEDIX develops innovative durable (to be used for several years) and disposable (replaced every 2-3 days) insulin pumps for helping diabetics manage their diabetes.
Insulin pumps deliver...
www.nilimed.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Hypoglycemia scientists - we have details of around 2388 individuals working on Hypoglycemia .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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