Hypopituitarism

Hypopituitarism is a medical term describing the deficiency of one or more hormones of the pituitary gland. The hypothalamus regulates pituitary secretion by the production of releasing hormones and posterior pituitary hormones and hence its dysfunction can also lead to hypopituitarism. In endocrinology, deficiency of one or multiple hormones of the anterior pituitary is generally referred to as hypopituitarism, while deficiency of the posterior lobe generally only leads to central diabetes insipidus. The deficiency of all anterior pituitary hormones is termed panhypopituitarism. (From the Wikpedia article Hypopituitarism.)

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Recent Publications on Hypopituitarism:
Pituitary and Stalk Lesions (Infundibulo-hypophysitis) Associated with Immunoglobulin G4-related Systemic Disease: an Emerging Clinical Entity. Inflammatory lesions of the pituitary gland are rarely encountered....	21st November, 2009	Clinical Research Institute, National Hospital Organization Kyoto Medical	Endocr J. 2009 Nov 19.
Absence of SIX3 mutations in patients with congenital hypopituitarism. Inflammatory lesions of the pituitary gland are rarely encountered....	19th November, 2009	Neural Development Unit, Institute of Child Health, University College	Am J Med Genet A. 2009 Nov 16. DOI Direct Link
Sheehan's syndrome and its impact on bone mineral density. INTRODUCTION: Although there have been few studies investigating...	12th November, 2009	Department of Endocrinology, Dicle University School of Medicine, 21280	Gynecol Endocrinol. 2009 May;25(5):344-9.
Analysis of empty sella secondary to the brain tumors. OBJECTIVE: The definition of empty sella syndrome is 'an anatomical entity...	7th November, 2009	Department of Neurosurgery, Konyang University Hospital, Daejeon, Korea.	J Korean Neurosurg Soc. 2009 Oct;46(4):355-9. Epub 2009 Oct 31. DOI Direct Link
Permanent central diabetes insipidus after mild traumatic brain injury. AIM: The patients in the permanent diabetes insipidus (DI) group are more...	7th November, 2009	Department of Physical Medicine and Rehabilitation, China Medical	Brain Inj. 2009 Dec;23(13-14):1095-8.
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Hypopituitarism Patents:
US Patent No.	Title
7268152	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
7358347	MEN1, the gene associated with multiple endocrine neoplasia type 1, menin polypeptides and uses thereof
7365077	Piperazine bis-amide derivatives and their use as antagonists of the orexin receptor
7368527	HADDE71 polypeptides
7368531	Human secreted proteins
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