Recent Publications on I-Kappa B Kinase: |  |
The human IKKbeta subunit kinase domain displays CK2-like phosphorylation specificity.
NF-kappaB activation in response to pro-inflammatory stimuli relies upon...
Direct Link | 6th September, 2008
| Structural Biochemistry Laboratory, Department of Chemistry &
|
Regulation of PPARgamma function by TNF-alpha.
The nuclear receptor PPARgamma is a lipid sensor that regulates lipid...
Direct Link | 6th September, 2008
| Pennington Biomedical Research Center, Louisiana State University System,
|
IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver.
Inflammatory destruction of intrahepatic bile ducts is a common cause of...
Direct Link | 4th September, 2008
| Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne
|
Phosphorylation of SNAP-23 by IkappaB kinase 2 regulates mast cell degranulation.
Mast cells are known to play a pivotal role in allergic diseases....
Direct Link | 3rd September, 2008
| Laboratory of Genetics, The Salk Institute, 10010 North Torrey Pines Road,
|
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis.
Hepatocyte I kappaB kinase beta (IKK beta) inhibits hepatocarcinogenesis...
Direct Link | 30th August, 2008
| Laboratory of Gene Regulation and Signal Transduction, Department of
|
BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells.
B cell activating factor (BAFF) signals through BAFF-R to promote mature B...
Direct Link | 21st August, 2008
| Immune Disease Institute, Harvard Medical School, Boston, MA 02115, USA.
|
Inhibition of Human Immunodeficiency Virus Type 1 Replication by Blocking I{kappa}B Kinase with Noraristeromycin.
Nuclear factor kappaB (NF-kappaB) is one of the critical transcription...
Direct Link | 21st August, 2008
| Department of Molecular and Cellular Biology, Nagoya City University
|
Cell signaling. "Make and brake" in signaling.
Purpose: Corneal ulcer results from excessive collagen degradation in the...
Direct Link | 14th August, 2008
| University of Crete Medical School and Institute for Molecular Biology and
|
Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.
Cytokine signaling is thought to require assembly of multicomponent...
Direct Link | 14th August, 2008
| Laboratory of Gene Regulation and Signal Transduction, Department of
|
| Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.
| 13th August, 2008
| Laboratory for Cell Signaling, RIKEN Research Center for Allergy and
|
| The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells.
| 13th August, 2008
| Departmentof Clinical Research, Laboratory of Cardiovascular Surgery,
|
RelB is differentially regulated by I{kappa}B-Kinase{alpha} (IKK{alpha}) in B Cells and Mouse Lung by Cigarette Smoke.
The transcription factor NF-kappaB activation is controlled by two main...
Direct Link | 9th August, 2008
| Department of Environmental Medicine, Lung Biology and Disease Program,
|
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
Berberine, an isoquinoline alkaloid derived from a plant used...
Direct Link | 6th August, 2008
| Department of Experimental Therapeutics, Cytokine Research Laboratory, The
|
Inhibition by a Selective I{kappa}B Kinase--2 Inhibitor of Interleukin-1--Induced Collagen Degradation by Corneal Fibroblasts in Three-Dimensional Culture.
Purpose: Corneal ulcer results from excessive collagen degradation in the...
Direct Link | 5th August, 2008
| Department of Ophthalmology, Yamaguchi University Graduate School of
|
Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress.
The transcription factor NF-kappaB has critical functions in biologic...
Direct Link | 31st July, 2008
| Department of Pharmacology, University of Wisconsin, Madison, WI 53706,
|
