Idoxuridine

Idoxuridine is an anti-herpesvirus antiviral drug.It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. (From the Wikpedia article Idoxuridine.)

Download PDF containing detailed information.

Recent Publications on Idoxuridine:
Synthesis and enzymatic incorporation of modified deoxyuridine triphosphates. We describe the synthesis of 2'-deoxyuridine-5'-triphosphate derivatives...	6th November, 2009	University College London, Department of Chemistry, 20 Gordon Street,	Org Biomol Chem. 2009 Sep 21;7(18):3826-35. Epub 2009 Jul 21. DOI Direct Link
Intracerebral delivery of 5-iodo-2'-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma. Iodine-enhanced synchrotron stereotactic radiotherapy takes advantage of...	6th November, 2009	INSERM U836, Equipe 6, Grenoble 38043, France.	J Synchrotron Radiat. 2009 Jul;16(Pt 4):573-81. Epub 2009 May 28. DOI Direct Link
Preparation and preliminary evaluation of novel beta-cyclodextrin/IUDR prodrug formulations. PURPOSE: Iododeoxyuridine (IUdR) has a very short in vivo half-life and...	29th April, 2009	Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta,	J Pharm Pharm Sci. 2008 Jun 18;11(2):32s-43s.
Periocular dermatitis: a report of 401 patients. BACKGROUND: Periocular contact dermatitis may appear as contact...	28th April, 2009	Faculty of Medicine, Department of Dermatology, Venerology and	J Eur Acad Dermatol Venereol. 2009 Feb;23(2):124-8. Epub 2008 Aug 29. DOI Direct Link
Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers. DNA damage processing by mismatch repair (MMR) and/or base excision repair...	17th April, 2009	Case Integrative Cancer Biology Program, Case Western Reserve University,	Clin Cancer Res. 2009 Mar 15;15(6):1853-9. Epub 2009 Feb 24. DOI Direct Link
→View more research publications.

Idoxuridine Patents:
US Patent No.	Title
7517912	Prostaglandin analog compositions and methods to treat epithelial-related conditions
7557190	Optimized proteins that target Ep-CAM
7560544	3,5-Disubsitituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof
7563899	(S)-N-methylnaltrexone
7566703	Semi-soft C-class immunostimulatory oligonucleotides
→View more patents.

BioPortfolio Ltd. offers e-mail and postal lists for Idoxuridine scientists - we have details of around 279 individuals working on Idoxuridine .