Idoxuridine

Idoxuridine is an anti-herpesvirus antiviral drug.It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. (From the Wikpedia article Idoxuridine.)

Download PDF

Recent Publications on Idoxuridine:
Enhanced experimental tumor metastasis with age in senescence-accelerated mouse. Tumor metastasis is affected by the host immune surveillance system. Since...	20th June, 2008	Department of Medical Biochemistry and Global COE Program, School of	Biol Pharm Bull. 2008 May;31(5):847-51.
Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine. BACKGROUND: The vaccinia virus (VV) F2L gene encodes a functional...	23rd April, 2008	Department of Pediatrics, University of Alabama School of Medicine,	Virol J. 2008 Mar 5;5:39. DOI Direct Link
Supported synthesis and functionnalization of 2''-deoxyuridine by Suzuki-Miyaura cross-coupling. The synthesis and modification of 2'-deoxyuridine has been realized under...	21st March, 2008	Institut de Chimie Organique et Analytique, UMR CNRS 6005, Universite	Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1395-8. DOI Direct Link
Characterization of mouse 3T3-swiss albino cells available in Japan: necessity of quality control when used as feeders. Mouse 3T3-Swiss albino cells are widely used as feeder cells to culture...	14th March, 2008	Center for Pathogen Genomics, National Institute of Infectious Diseases,	Jpn J Infect Dis. 2008 Jan;61(1):9-12.
Replication labeling with halogenated thymidine analogs. In this unit, several basic protocols to identify sites of DNA replication...	21st February, 2008	Department of Biological Science Florida State University Tallahassee,	Curr Protoc Cell Biol. 2007 Jun;Chapter 22:Unit 22.10. DOI Direct Link
→View more research publications.

Idoxuridine Clinical Trials:
PET Scans in Patients With Locally Advanced Breast Cancer	Breast Cancer
IUdR/BUdR Cell Cycle Labelling	Hematologic Malignancies
Validation of 18F-MISO-PET and 18F-FLT-PET	Head and Neck Neoplasms

Idoxuridine Patents:
US Patent No.	Title
7205404	Phosphorus-containing prodrugs
7272440	Method and apparatus for treatment of viral diseases
7276506	Immunosuppressive effects of pteridine derivatives
7288265	Treating viral infection at smallpox vaccination site
7291497	Medical device for analyte monitoring and drug delivery
→View more patents.

BioPortfolio Ltd. offers e-mail and postal lists for Idoxuridine scientists - we have details of around 279 individuals working on Idoxuridine .

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.  See User Agreement

Send comments and feedback to:
Peter Barfoot Managing Director, BioPortfolio Ltd.
UK Tel: (+44) 1300 321501
USA Voicemail and Fax: (+1) 415 680 2472

All rights reserved. All other trademarks recognized.

BioPortfolio Limited is registered in England & Wales at Wessex Barn, Dorchester Road, Frampton, Dorset, DT2 9NB, UK. No.3312883 VAT No. GB 744 6483 10

Copyright 1997-2008 - BioPortfolio Limited.