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Iduronate Sulfatase

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Recent Publications on Iduronate Sulfatase:

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Mortality and cause of death in mucopolysaccharidosis type II-a historical review based on data from the Hunter Outcome Survey (HOS).
Mucopolysaccharidosis type II (MPS II or Hunter syndrome) is a...		17th November, 2009
Willink Unit, Genetic Medicine, Manchester Academic Health Science Centre, J Inherit Metab Dis. 2009 Aug;32(4):534-43. Epub 2009 Jul 14.
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Clinical and biochemical studies in mucopolysaccharidosis type II carriers.
The aim of the study was to characterize clinically and biochemically...		13th October, 2009
Department of Genetics, J Inherit Metab Dis. 2009 Oct 10.
DOI Direct Link
Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis.
Iduronate-2-sulfatase (IDS) is a lysosomal enzyme expressed in pancreatic...		1st October, 2009
Endocrinology and Diabetes Unit, Laboratory of Diabetes and Obesity, Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E793-801. Epub 2009 Jul 14.
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IDS crossing of the blood-brain barrier corrects CNS defects in MPSII mice.
Mucopolysaccharidosis type II (MPSII), or Hunter syndrome, arises from a...		24th September, 2009
Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy. Am J Hum Genet. 2009 Aug;85(2):296-301.
DOI Direct Link
A novel functional role of iduronate-2-sulfatase in zebrafish early development.
Sulfated glycosaminoglycan chains of extracellular matrix and cell...		19th September, 2009
Department of Biology, University of Padova, 35131, Italy. Matrix Biol. 2009 Sep 15.
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Press Releases About Iduronate Sulfatase:

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Biotech Tracker: TKT’s I2S Trial Moving Forward 1st January, 1970 Biotracker
Biotech Tracker: TKT’s I2S Trial Moving Forward March

Iduronate Sulfatase Patents:

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US Patent No.Title
6423312 Compositions including glycosaminoglycans degrading enzymes and use of same against surface protected bacteria
6979563 Attenuation of tumor growth, metastasis and angiogenesis
7018628 Vectors derived from baculovirus and use for transferring nucleic acids into nerve cells of vertebrates
7034010 Use of recombinant gene delivery vectors for treating or preventing lysosomal storage disorders
7045508 Use of rapamycin to inhibit immune response and induce tolerance to gene therapy vector and encoded transgene products

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BioPortfolio Ltd. offers e-mail and postal lists for Iduronate Sulfatase scientists - we have details of around 24 individuals working on Iduronate Sulfatase .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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