Recent Publications on Immunoglobulin Class Switching: |  |
| IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.
| 20th August, 2008
| Immunology and Inflammation Group, Garvan Institute of Medical Research,
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| The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice.
| 20th August, 2008
| Division of Rheumatology and Immunology, Department of Medicine, Medical
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A fundamental role for interleukin-21 in the generation of T follicular helper cells.
T cell help to B cells is a fundamental property of adaptive immunity, yet...
Direct Link | 13th August, 2008
| Department of Immunology, Garvan Institute of Medical Research, 384
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Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice.
OBJECTIVE: Systemic lupus erythematosus is a multifactorial disease with a...
Direct Link | 9th August, 2008
| Molecular Genetics and Rheumatology Section, Faculty of Medicine, Imperial
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| Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.
| 29th July, 2008
| Department of Pathology and Laboratory Medicine, Weill Graduate School of
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A role for DRAK2 in the germinal center reaction and the antibody response.
DAP-related apoptotic kinase-2 (DRAK2), a death-associated protein kinase...
Direct Link | 22nd July, 2008
| Center for Immunology, University of California, Irvine, CA, USA.
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MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
MicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of...
Direct Link | 8th July, 2008
| Laboratory of Molecular Immunology, The Rockefeller University, New York,
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MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.
B lymphocytes perform somatic hypermutation and class-switch recombination...
Direct Link | 8th July, 2008
| Laboratory of Lymphocyte Biology, The Rockefeller University, 1230 York
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Recurrent inactivation of the PRDM1 gene in primary central nervous system lymphoma.
Primary lymphomas of the CNS (PCNSLs) show molecular features of the late...
Direct Link | 4th July, 2008
| Department of Neuropathology, University Hospital of Cologne, Kerpener
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| Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells.
| 2nd July, 2008
| Department of Microbiology and Immunology, University of Miami, Miller
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B-cell maturation defects in common variable immunodeficiency and association with clinical features.
AIMS: Patients with common variable immunodeficiency (CVID) often have...
Direct Link | 25th June, 2008
| Institute of Clinical Pathology and Medical Research, Westmead Hospital,
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The regulation of IgA class switching.
IgA class switching is the process whereby B cells acquire the expression...
Direct Link | 18th June, 2008
| Department of Pathology and Laboratory Medicine, Weill Medical College of
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Detection of isotype switch rearrangement in bulk culture by PCR.
When a B lymphocyte changes from synthesizing IgM to synthesizing IgG,...
Direct Link | 18th June, 2008
| Center for Biologics Evaluation and Research, Food and Drug
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Profound hypogammaglobulinemia 7 years after treatment for indolent lymphoma.
We report a case of a previously healthy 31 year old woman diagnosed with...
Direct Link | 3rd June, 2008
| University of Rochester, Hematology/Oncology, Rochester, New York 14642,
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Control of IL-4 expression in T helper 1 and 2 cells.
The mechanism of differentiation of naive T cells to a variety of effector...
Direct Link | 16th May, 2008
| King's College London, MRC and Asthma UK Centre in Allergic Mechanisms of
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