Immunophenotyping

Immunophenotyping is a technique used to study the protein expressed by cells. This technique is commonly used in basic science research and laboratory diagnostic purpose. This can be done on tissue section , cell suspension, etc. An example is the diagnosis of leukemia. It involves the labelling of white blood cells with antibodies directed against surface proteins on their membrane. By choosing appropriate antibodies, the differentiation of leukemic cells can be accurately determined. The labelled cells are processed in a flow cytometer, a laser-based instrument capable of analyzing thousands of cells per second. The whole procedure can be performed on cells from the blood, bone marrow or spinal fluid in a matter of a few hours.An Example of Information provided through Immnunophenotyping"The flow cytometric immunophenotyping report indicated the malignant cells were positive for CD19, CD10, dimCD20, CD45, HLA-DR, and λ immunoglobulin light chain. There was no coexpression of CD5 or CD23 by the monoclonal B-cell population." (From the Wikpedia article Immunophenotyping.)

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Recent Publications on Immunophenotyping:
CD23+ Mantle Cell Lymphoma: A Clinical Pathologic Entity Associated With Superior Outcome Compared With CD23- Disease. Mantle cell lymphoma (MCL) commonly lacks expression of CD23. However, a...	17th July, 2008	Departments of Pathology, Northwestern University Feinberg School of	Am J Clin Pathol. 2008 Aug;130(2):166-77. DOI Direct Link
Disproportionally strong increase of B cells in inflammatory cerebrospinal fluid of dogs with Steroid-responsive Meningitis-Arteritis. Steroid-responsive Meningitis-Arteritis (SRMA) is a systemic inflammatory...	16th July, 2008	Department of Small Animal Medicine and Surgery, School of Veterinary	Vet Immunol Immunopathol. 2008 Jun 6;. DOI Direct Link
Characterization of childhood precursor T-lymphoblastic lymphoma by immunophenotyping and fluorescent in situ hybridization: A report from the Children's Oncology Group. BACKGROUND: T-lymphoblastic lymphoma (T-LBL) accounts for 25-30% of...	12th July, 2008	Department of Pathology, University of Utah Health Sciences Center, ARUP	Pediatr Blood Cancer. 2008 Jul 10;. DOI Direct Link
Predictive value of blood and bone marrow flow cytometry in B-cell lymphoma classification: comparative analysis of flow cytometry and tissue biopsy in 252 patients. OBJECTIVE: To study the effectiveness of peripheral blood (PB) and bone...	11th July, 2008	Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA.	Mayo Clin Proc. 2008 Jul;83(7):776-85.
Report of proceedings of the national meeting on "Guidelines for Immunophenotyping of Hematolymphoid Neoplasms by Flow Cytometry". Background: Immunophenotyping of hematolymphoid neoplasms is being done in...	8th July, 2008	Department of Pathology, Tata Memorial Hospital, Mumbai, India.	Indian J Pathol Microbiol. 2008 Apr;51(2):161-6.
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BioNews Results for Immunophenotyping:
Immunophenotyping of serous carcinoma of the female genital tract	Nature:  Jun 20 2008 4:54PM Matching: immunophenotyping

Immunophenotyping Clinical Trials:
Treatment With Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs	HIV Infections

Immunophenotyping Patents:
US Patent No.	Title
7272252	Automated system for combining bright field and fluorescent microscopy
7312086	Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
7324926	Methods for predicting chemosensitivity or chemoresistance
7326577	Cell fixation and use in phospho-proteome screening
7326781	Polynucleotides encoding the human citron kinase polypeptide, BMSNKC.sub.--0020/0021
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Companies working in the area of Immunophenotyping from Bioportfolio's Biocorporate database :
Company Name
BioLegend BioLegend develops and manufactures world-class, cutting-edge immunological reagents for biomedical research, offered at an outstanding value. Our product areas include cell immunophenotyping,... www.biolegend.com/        View full profile

BioPortfolio Ltd. offers e-mail and postal lists for Immunophenotyping scientists - we have details of around 1709 individuals working on Immunophenotyping .

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