Recent Publications on Immunophilins: |  |
| Computational anti-AIDS drug design based on the analysis of the specific interactions between immunophilins and the HIV-1 gp120 V3 loop. Application to the FK506-binding protein.
| 24th September, 2008
| Institute of Bioorganic Chemistry, National Academy of Sciences of
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Kaempferol: a new immunosuppressant of calcineurin.
Calcineurin (CN), the Ca(2+)/calmodulin (CaM)-dependant protein...
Direct Link | 23rd September, 2008
| Department of Biochemistry and Molecular Biology, Beijing Normal
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Modulation of P-glycoproteins by auxin transport inhibitors is mediated by interaction with immunophilins.
The immunophilin-like FKBP42 TWISTED DWARF1 (TWD1) has been shown to...
Direct Link | 23rd September, 2008
| Institute of Plant Biology and Zurich-Basel Plant Science Center,
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Spliceosomal immunophilins.
The spliceosome is a dynamic, macromolecular complex, which removes...
Direct Link | 9th September, 2008
| Florida International University, Department of Biological Sciences,
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| Pharmacodynamic monitoring of calcineurin phosphatase activity in transplant patients treated with calcineurin inhibitors.
| 8th August, 2008
| Department of Clinical Pharmacy and Education, Graduate School of
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A novel FK506-like binding protein (FKBPL) interacts with the glucocorticoid receptor and regulates steroid receptor signalling.
FKBPL is a novel immunophilin-like protein that plays a role in the...
Direct Link | 2nd August, 2008
| School of Pharmacy, Queen's University, 97 Lisburn Road, Belfast, Northern
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FKBP Family Proteins: Immunophilins with Versatile Biological Functions.
Immunophilins consist of a family of highly conserved proteins binding...
Direct Link | 19th July, 2008
| School of Biological Science, Nanyang Technological University, Singapore,
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Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: heat shock protein 70 levels are modulated in microglial cells.
Functional loss after spinal cord injuries is originated by primary and...
Direct Link | 26th June, 2008
| Group of Neuroplasticity and Regeneration, Institute of Neurosciences and
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Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.
The GNOM protein plays a fundamental role in Arabidopsis thaliana...
Direct Link | 16th May, 2008
| Center of Molecular Biology of Plants, University of Tubingen, 72076
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| FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway.
| 7th May, 2008
| Hermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford
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| Pharmacological neuroprotective therapy for acute spinal cord injury: state of the art.
| 26th April, 2008
| Unidad de Investigacion Medica en Enfermedades Neurologicas, HE, CMN Siglo
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Emerging neuromodulatory molecules for the treatment of neurogenic erectile dysfunction caused by cavernous nerve injury.
Advances in the neurobiology of growth factors, neural development, and...
Direct Link | 19th April, 2008
| The Ottawa Hospital, Civic Campus, B3-Division of Urology, Ottawa K1Y 4E9,
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Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4(+) T cells.
Cell-free human T-lymphotropic virus type 1 (HTLV-1) virions are poorly...
Direct Link | 17th April, 2008
| Basic Research Program, Science Applications International
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Neuroprotective and antiretroviral effects of the immunophilin ligand GPI 1046.
HIV infection results in a neurodegenerative disorder for which currently...
Direct Link | 26th February, 2008
| Department of Neurology, The Johns Hopkins University School of Medicine
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Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities.
Rapamycin is an immunosuppressive immunophilin ligand reported as having...
Direct Link | 6th February, 2008
| Chemical and Screening Sciences, Wyeth Research, 401 North Middletown
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