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Keloid

A keloid is a type of scar which results in an overgrowth of tissue at the site of a healed skin injury. Keloids are firm, rubbery lesions or shiny, fibrous nodules and can vary from pink to flesh-colored or red to dark brown in color. A keloid scar is benign, non-contagious and usually accompanied by severe itchiness, sharp pains and changes in texture. In severe cases, it can affect movement of skin. Keloids should not be confused with hypertrophic scars, which are raised scars that do not grow beyond the boundaries of the original wound and may reduce over time. (From the Wikpedia article Keloid.)

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Recent Publications on Keloid:

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TGF-beta1 antisense therapy modulates expression of matrix metalloproteinases in keloid-derived fibroblasts.
Transforming growth factor-beta1 (TGF-beta1) has been identified as an...
26th June, 2008
Department of Otolaryngology, Head and Neck Surgery, University Hospital Int J Mol Med. 2008 Jul;22(1):55-60.
[Pharmacological therapy of keloids in an athymic mouse model]
PURPOSE: In spite of the high incidence of dermal fibroproliferative...
21st June, 2008
Abteilung fur Plastische Chirurgie und Handchirurgie, DRK-Kliniken Handchir Mikrochir Plast Chir. 2008 Apr;40(2):81-7.
DOI Direct Link
Association of HLA-DQA1 and DQB1 alleles with keloids in Chinese Hans.
BACKGROUND: Some studies have suggested that human HLA status might...
20th June, 2008
Institute of Dermatology & Department of Dermatology, The First Hospital, J Dermatol Sci. 2008 Jun 16;.
DOI Direct Link
Should excised keloid scars be sent for routine histologic analysis?
BACKGROUND: Effective measures are lacking to treat long-term poorly...
20th June, 2008
Ann Plast Surg. 2008 Jun;60(6):724.
DOI Direct Link
[Expression of periostin and the effect of hydrocortisone on it in human fibroblasts of scar.]
OBJECTIVE:To probe into the role of periostin in the formation of scars...
19th June, 2008
Department of Plastic Surgery, Peking University Third Hospital, Beijing Beijing Da Xue Xue Bao. 2008 Jun 18;40(3):301-5.

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BioNews Results for Keloid:

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Radiation Therapy for Neovascular Age-related Macular Degeneration
Retinal Physician:  Jun 15 2008 1:45PM Matching: keloid
Method of delivering therapeutic agents to site of tissue injury
PharmCast:  Apr 14 2008 4:21AM Matching: keloid

Keloid Clinical Trials:

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A Randomized Clinical Study Comparing Two Closure Techniques of Excised Keloids
Keloid Interventions: Procedure: Suture;   Device: Clozex
Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars
Scar Intervention: Procedure: pulsed dye laser therapy
Safety and Efficacy of Different Intervals of Pulsed Dye Laser Sessions on Improvement of Surgical Scars
Scar Intervention: Procedure: pulsed dye laser therapy
Prospective Randomized Trial: Curettage Versus Excision in Nodular and Superficial Basal Cell Carcinomas
Carcinoma, Basal Cell
A Post-Market Study to Evaluate Adverse Event Incidence Rates in Patients With Skin of Color Undergoing Correction of Nasolabial Folds With Hylaform, Hylaform Plus and Captique.
Facial Wrinkles

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Keloid Patents:

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US Patent No.Title
7332305 Genetic polymorphism in the Zf9 gene linked to inappropriate scarring or fibrosis
7345148 Human G-protein coupled receptor, HGPRBMY29sv1 polypeptides
7348331 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones
7348336 Substituted .beta.-carbolines
7348418 Carcinoma-related genes and polypeptides and methods of use thereof

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Companies working in the area of Keloid from Bioportfolio's Biocorporate database :

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Company Name

Life Medical Sciences Incorporated

Life Medical Sciences, Inc. is a biomaterials company engaged in the development and commercialization of innovative and cost-effective medical devices for therapeutic applications. During 1998, the...
www.Lifemed.com/        View full profile
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Orthologic

OrthoLogic is a biotechnology company committed to developing a pipeline of novel peptides and other molecules aimed at helping patients with under-served conditions. The Company is focused on the...
www.orthologic.com/        View full profile
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Biodermis

Seventeen years ago, Biodermis was first to introduce a revolutionary technology that set the standard for scar management, and spawned the evolution of the gel sheeting industry as we know it today....
www.biodermis.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Keloid scientists - we have details of around 239 individuals working on Keloid .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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