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Keratoconjunctivitis

Keratoconjunctivitis refers to an inflammation of the cornea and conjunctiva.When only the cornea is inflamed, it is called keratitis; when only the conjunctiva is inflamed, it is called conjunctivitis.There several potential causes of the inflammation:* Keratoconjunctivitis sicca is used when the inflammation is due to dryness. * The term "Vernal keratoconjunctivitis" is used to refer to keratoconjunctivitis occurring in spring, and is usually considered to be due to allergens.* "Atopic keratoconjunctivitis" is one manifestation of atopy.* "Epidemic keratoconjunctivitis" is caused by an adenovirus infection.* "Infectious bovine keratoconjunctivitis" is a disease affecting cattle caused by the bacteria Moraxella bovis.* "Superior limbic keratoconjuctivitis" is thought to be caused by mechanical trauma.* "Keratoconjunctivitis photoelectrica" means that the inflammation is caused by UV light. This can be caused, by example, by welding without wearing protective eye glass. The inflammation will only appear after about 6 to 12 hours. It can be treated by rest . Additionally, one can wear sunglasses. Antibiotics are not proven to be helpful, however oxybuprocaine may help. (From the Wikpedia article Keratoconjunctivitis.)

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Recent Publications on Keratoconjunctivitis:

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[Mechanism of onset and treatment in allergic conjunctival disease: cedar pollinosis and vernal keratoconjunctivitis.]
BACKGROUND: It has become evident that resident stromal cells, such as...
11th November, 2009
Dept. of Ophthalmology, Tokyo Women's Medical University. Arerugi. 2009 Oct;58(10):1401-6.
Vernal keratoconjunctivitis-A rare but serious comorbidity of allergic rhinitis and eustachian tube dysfunction.
OBJECTIVE: To determine the prevalence of symptoms and signs of allergic...
11th November, 2009
Department of Otolaryngology Head and Neck Surgery, Selcuk University, Int J Pediatr Otorhinolaryngol. 2009 Nov 7.
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Cyclosporin A eye drops inhibit fibrosis and inflammatory cell infiltration in murine type I allergic conjunctivitis without affecting the early-phase reaction.
PURPOSE: To understand the mechanisms of action of cyclosporin A eye drops...
11th November, 2009
Research and Development Center, Santen Pharmaceutical Co., Ltd., 8916-16 Curr Eye Res. 2009 Jun;34(6):426-37.
[Ophthalmology]
Allergic conjunctival diseases caused by immediate hypersensitivity are...
11th November, 2009
Department of Ophthalmology, Tokyo Women's Medical University, School of Nippon Rinsho. 2009 Nov;67(11):2157-61.
Effect of bovine respiratory disease and overall pathogenic disease incidence on carcass traits.
The objective this study was to evaluate the effects of incidence of...
10th November, 2009
U.S. Meat Animal Research Center, USDA, ARS, Clay Center, NE 68933. J Anim Sci. 2009 Nov 6.
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BioNews Results for Keratoconjunctivitis:

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Conjunctival Fixation Sutures for Refractory Superior Limbic Keratoconjunctivitis
British Journal of Ophthalmology:  Oct 14 2009 11:43PM Matching: keratoconjunctivitis

Keratoconjunctivitis Clinical Trials:

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Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis

Keratoconjunctivitis Patents:

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US Patent No.Title
7541362 Heterocyclic dihydropyrimidine compounds
7572442 Selected antibody compositions for binding to aminophospholipids
7572448 Combined cancer treatment methods using selected antibodies to aminophospholipids
7572781 Prodrugs for use as ophthalmic agents
7572811 Immunosuppressant compounds and compositions

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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