Keratoconus

Keratoconus , is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to thin and change to a more conical shape than its normal gradual curve. Keratoconus can cause substantial distortion of vision, with multiple images, streaking and sensitivity to light all often reported by the patient. Keratoconus is the most common dystrophy of the cornea, affecting around one person in a thousand, and it seems to occur in populations throughout the world, although some ethnic groups experience a greater prevalence than others. It is typically diagnosed in the patient's adolescent years and attains its most severe state in the twenties and thirties.Keratoconus is a little-understood disease with an uncertain cause, and its progression following diagnosis is unpredictable. If afflicting both eyes, the deterioration in vision can affect the patient's ability to drive a car or read normal print. In most cases, corrective lenses are effective enough to allow the patient to continue to drive legally and likewise function normally. Further progression of the disease may require surgery including transplantation of the cornea. Despite its uncertainties, keratoconus can be successfully managed with a variety of clinical and surgical techniques, and often with little or no impairment to the patient's quality of life. (From the Wikpedia article Keratoconus.)

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Recent Publications on Keratoconus:
Induction of controlled wound healing with PMMA segments in the deep stroma in corneas of hens. Purpose. Polymethylmethacrylate (PMMA) segments are normally used in...	21st November, 2009		Eur J Ophthalmol. 2009 Nov 13.
Penetrating Keratoplasty for Unilateral Corneal Disease: Outcomes From a Tertiary Care Hospital in Australia. PURPOSE:: To assess the visual outcome after unilateral penetrating...	21st November, 2009	From the Department of Ophthalmology (V.J., S.M., J.B., R.B.V.), Royal	Eye Contact Lens. 2009 Nov 17. DOI Direct Link
Location of Steepest Corneal Area of Cone in Keratoconus Stratified by Age Using Pentacam. PURPOSE:To evaluate topographic patterns in keratoconic cases and to...	20th November, 2009		J Refract Surg. 2009 Nov 1;25(11):1012-1016. doi: DOI Direct Link
Neural contrast sensitivity calculated from measured total contrast sensitivity and modulation transfer function. Abstract. Purpose: To test the feasibility of calculating neural contrast...	17th November, 2009	Institut Universitari Barraquer, Universitat Autonoma de Barcelona, Spain.	Acta Ophthalmol. 2009 Nov 11. DOI Direct Link
Keratoconus detection using corneal topography. PURPOSETo review the topographic patterns associated with keratoconus...	17th November, 2009	Baylor College	J Refract Surg. 2009 Oct;25(10 Suppl):S958-62. doi: DOI Direct Link
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Press Releases About Keratoconus:
Menicon to Acquire David Thomas Contact Lenses Ltd., Major U.K. Custom Lens Manufacturer	19th November, 2009		NAGOYA, Japan, November 19 /PRNewswire/ -- Menicon Co., Ltd. (Menicon) and David Thomas Contact Lenses Ltd. (DTCL) announced on November 19 that the two companies reached agreement on November 16,
CONNECT(R) Announces ClearKone(TM) by SynergEyes(R) As Finalist for Most Innovative New Product Award	21st October, 2009	SynergEyes, Inc.	CARLSBAD, Calif., Oct. 21 /PRNewswire/ -- CONNECT(R), a non-profit organization dedicated to creating and sustaining the growth of innovative technology and life science businesses in San Diego,
SynergEyes(R) Launches a New Website for Keratoconus Patients	11th March, 2009	SynergEyes, Inc.	CARLSBAD, Calif., March 11 /PRNewswire/ -- SynergEyes, Inc., the developer of the first FDA-cleared hybrid contact lens specifically designed for patients with keratoconus, has launched a new
New Vitamin Treatment Saves Patients (Including a U.S. Olympic Athlete) from Blinding Eye Disease Without Surgery	3rd March, 2009	Dr. Brian S. Boxer Wachler, MD	LOS ANGELES, March 3 /PRNewswire/ -- Dr. Brian S. Boxer Wachler, MD, a world-renowned eye surgeon and the director of the Boxer Wachler Vision Institute in Beverly Hills, California, announced today

BioNews Results for Keratoconus:
CONNECT(R) Announces ClearKone(TM) by SynergEyes(R) As Finalist for Most Innovative New Product Award	TickerTech.com:  Oct 21 2009 1:25PM Matching: keratoconus
Keratoconus: Time to Rewrite the Textbooks	Review of Ophthalmology:  Oct 20 2009 8:11PM Matching: keratoconus
Collagen cross-linkage: a comprehensive review and directions for future research	British Journal of Ophthalmology:  Oct 14 2009 11:36PM Matching: keratoconus
Keratoconus Complicated by Acute Corneal Hydrops	New England Journal of Medicine:  Oct 14 2009 9:25PM Matching: keratoconus

Keratoconus Patents:
US Patent No.	Title
7232568	Compositions and methods for treating hyperimmune response in the eye
7355793	Optical system applicable to improving the dynamic range of Shack-Hartmann sensors
7360892	Method and apparatus for selecting contact lens for reshaping altered corneas due to post refractive surgery, previous Ortho-K or Keratoconus
7365893	Iterative Fourier reconstruction for laser surgery and other optical applications
7365917	Optical method and system for extended depth of focus
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BioPortfolio Ltd. offers e-mail and postal lists for Keratoconus scientists - we have details of around 269 individuals working on Keratoconus .