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Keratoconus

Keratoconus , is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to thin and change to a more conical shape than its normal gradual curve. Keratoconus can cause substantial distortion of vision, with multiple images, streaking and sensitivity to light all often reported by the patient. Keratoconus is the most common dystrophy of the cornea, affecting around one person in a thousand, and it seems to occur in populations throughout the world, although some ethnic groups experience a greater prevalence than others. It is typically diagnosed in the patient's adolescent years and attains its most severe state in the twenties and thirties.Keratoconus is a little-understood disease with an uncertain cause, and its progression following diagnosis is unpredictable. If afflicting both eyes, the deterioration in vision can affect the patient's ability to drive a car or read normal print. In most cases, corrective lenses are effective enough to allow the patient to continue to drive legally and likewise function normally. Further progression of the disease may require surgery including transplantation of the cornea. Despite its uncertainties, keratoconus can be successfully managed with a variety of clinical and surgical techniques, and often with little or no impairment to the patient's quality of life. (From the Wikpedia article Keratoconus.)

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Recent Publications on Keratoconus:

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Aliphatic beta-nitro alcohols for non-enzymatic collagen cross-linking of scleral tissue.
The success of riboflavin photochemical cross-linking of the cornea in...
12th July, 2008
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia Exp Eye Res. 2008 Jun 19;.
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Superior keratoconus with hydrops.
Superior keratoconus is a rare form of keratoconus, in which the corneal...
11th July, 2008
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Int Ophthalmol. 2008 Jul 10;.
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[Collagen cross-linking with riboflavin and UVA light in keratoconus - results from Dresden.]
PURPOSE: The aim of this long-term retrospective study was to prove a...
8th July, 2008
Augenklinik, Universitatsklinikum, Fetscherstrasse 74, 01307, Dresden, Ophthalmologe. 2008 Jul 6;.
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Aberrometry in clinical practice: Case series.
The application of aberrometry in the field of refractive surgery has led...
8th July, 2008
Faculty of Life Sciences, University of Manchester, Manchester M60 1QD, Cont Lens Anterior Eye. 2008 Jul 3;.
DOI Direct Link
[Confocal microscopy of the cornea. Communication 2. Morphological changes in keratoconus]
The paper presents the results of studying morphological changes in...
1st July, 2008
Vestn Oftalmol. 2008 May-Jun;124(3):6-10.

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BioNews Results for Keratoconus:

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Certain office visits for contact lens patients can be billed as 'medical'
PCON SuperSite:  Jul 8 2008 2:44PM Matching: keratoconus
Keratoconus - Recent findings in keratoconus described by researchers from University of Auckland
NewsRX:  Jun 25 2008 3:43PM Matching: keratoconus
Measure of Keratoconus Progression Using Orbscan II
PCON SuperSite:  Jun 12 2008 9:43PM Matching: keratoconus

Keratoconus Clinical Trials:

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Intacs for Keratoconus
Outcomes in a Comparison of Manual Penetrating Keratoplasty and the IntraLase® Enabled Keratoplasty
Keratoconus Interventions: Procedure: Penetrating keratoplasty with IntraLase;   Procedure: Penetrating keratoplasty with vacuum trephine
Corneal Topographer Fluorescein Patterns
Keratoconus Intervention: Other: Comparison of fluorescein patterns
Lamellar Transplant With Lyophilized Corneas
Evaluating Collagen Cross-Linking (CCL) Treatment in Norway
Keratoconus Interventions: Procedure: corneal cross-linking (CCL);   Drug: Riboflavin/dextran eyedrops;   Device: UV-X system

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Keratoconus Patents:

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US Patent No.Title
7078060 Solutions and aerosols of metal-containing compounds
7138432 Arylsulfonamido-substituted hydroxamic acid derivatives
7154111 Cornea characteristics measuring device
7168807 Iterative fourier reconstruction for laser surgery and other optical applications
7175278 Wavefront reconstruction using fourier transformation and direct integration

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BioPortfolio Ltd. offers e-mail and postal lists for Keratoconus scientists - we have details of around 269 individuals working on Keratoconus .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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