Recent Publications on L-Gulonolactone Oxidase: |  |
Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid.
Oxidative stress is implicated in the cognitive deterioration associated...
Direct Link | 16th September, 2008
| Division of Diabetes, Endocrinology & Metabolism, Vanderbilt University,
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The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease.
Humans have relatively low plasma ascorbate levels and high serum uric...
Direct Link | 4th September, 2008
| Division of Nephrology, Hypertension and Transplantation, University of
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Vitamin C supplementation does not protect L-gulono-gamma-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy.
In human studies, low vitamin C intake has been associated with more...
Direct Link | 1st February, 2008
| Division of Comparative Medicine, Massachusetts Institute of Technology,
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| Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency.
| 3rd January, 2008
| Department of Biology, University of Memphis, Memphis, TN, USA.
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Isolation and characterization of cDNA sequences of L-gulono-gamma-lactone oxidase, a key enzyme for biosynthesis of ascorbic acid, from extant primitive fish groups.
Most advanced teleosts lack L-gulono-gamma-lactone oxidase (GULO), a key...
Direct Link | 14th December, 2007
| Department of Aquaculture, Pukyong National University, Busan 608-737,
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Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha.
Some cells, including neutrophils, accumulate high intracellular ascorbate...
Direct Link | 10th November, 2007
| Free Radical Research Group, Pathology Department, Christchurch School of
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Sexual difference in ascorbic acid synthesis, tissue ascorbic acid and plasma total antioxidant capacity in mature chickens.
1. An experiment was conducted with commercial White Leghorn type chickens...
Direct Link | 1st November, 2007
| Department of Animal and Veterinary Sciences, Clemson University, Clemson,
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Effect of chronic oxidative/corticosterone-induced stress on ascorbic acid metabolism and total antioxidant capacity in chickens (Gallus gallus domesticus).
The consequences of chronic corticosterone-induced stress (CCIS) on...
Direct Link | 26th September, 2007
| Department of Animal and Veterinary Sciences, Clemson University, Clemson,
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Successful genetic transformation of Chinese cabbage using phosphomannose isomerase as a selection marker.
A mannose selection system was adapted for use in the...
Direct Link | 2nd May, 2007
| Department of Plant Resources, Sangju National University, Sangju,
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Vitamin C. Biosynthesis, recycling and degradation in mammals.
Vitamin C, a reducing agent and antioxidant, is a cofactor in reactions...
Direct Link | 7th April, 2007
| Universite Catholique de Louvain, Christian de Duve Institute of Cellular
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| Depletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model.
| 14th March, 2007
| Molecular Targets Program, Medical Oncology, James Graham Brown Cancer
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Dietary ascorbic acid may be necessary for enhancing the immune response in Siberian sturgeon (Acipenser baerii), a species capable of ascorbic acid biosynthesis.
Siberian sturgeon (Acipenser baerii Brandt) is one of few fish species...
Direct Link | 9th December, 2006
| Ministry of Education Key Laboratory of Biodiversity Science and
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Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase.
The last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants...
Direct Link | 4th November, 2006
| Laboratory of Mycobacterial Biochemistry, Pasteur Institute of Brussels,
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| Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice.
| 28th October, 2006
| Department of Nutrition, University of North Carolina, Chapel Hill, NC
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Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells.
As a primary antioxidant, ascorbic acid (AA) provides beneficial effects...
Direct Link | 17th August, 2006
| Department of Molecular Medicine, Kyungpook National University School of
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