Lactase

Lactase , a member of the β-galactosidase family of enzymes, is a glycoside hydrolase involved in the hydrolysis of the disaccharide lactose into constituent galactose and glucose monomers. In humans, lactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine.Lactase is essential for digestive hydrolysis of lactose in milk. Deficiency of the enzyme causes lactose intolerance.The optimum temperature for lactase is about 48 °C for its activity and has an optimum pH of 6.5. (From the Wikpedia article Lactase.)

Download PDF

Recent Publications on Lactase:
SODIUM TUNGSTATE DECREASES SUCRASE AND Na+/D-GLUCOSE COTRANSPORTER IN THE JEJUNUM OF DIABETIC RATS. Sodium tungstate reduces glycemia and reverts the diabetic phenotype in...	12th July, 2008	Departament de Fisiologia (Farmacia& Institut de Recerca de la Nutricio i	Am J Physiol Gastrointest Liver Physiol. 2008 Jul 10;. DOI Direct Link
Can primary hypolactasia manifest itself after the age of 20 years? A two-decade follow-up study. Objective. The age at manifestation of primary hypolactasia varies between...	9th July, 2008	Valio Ltd., Helsinki, Finland.	Scand J Gastroenterol. 2008 Apr 30;:1-6. DOI Direct Link
Genetic testing for adult-type hypolactasia in Italian families. Abstract Background: Adult-type hypolactasia is characterized by the...	9th July, 2008	1Department of Mother and Child, Biology and Genetics, University of	Clin Chem Lab Med. 2008 May 21;. DOI Direct Link
Lactase Production by Solid-state Cultivation of Kluyveromyces marxianus CDBBL 278 on an Inert Support: Effect of Inoculum, Buffer, and Nitrogen Source. A study was carried out to select the conditions for cultivation of...	2nd July, 2008	Departamento de Biotecnologia, Universidad Autonoma Metropolitana	Appl Biochem Biotechnol. 2008 Jul 1;. DOI Direct Link
Production, purification, and characterization of a potential thermostable galactosidase for milk lactose hydrolysis from Bacillus stearothermophilus. Beta-galactosidase, commonly named lactase, is one of the most important...	1st July, 2008	State Key Laboratory of Food Science and Technology, School of Food	J Dairy Sci. 2008 May;91(5):1751-8. DOI Direct Link
→View more research publications.

Lactase Clinical Trials:
Effects of Lactose on Fecal Microflora	Effect of Lactose-Lactase Interaction on Microflora Interventions: Dietary Supplement: lactose;   Dietary Supplement: lactose
Diagnostic Strategies in Patients Suspected of Irritable Bowel Syndrome	Irritable Bowel Syndrome

Lactase Patents:
US Patent No.	Title
7303871	Enzyme treatment of foodstuffs for Celiac Sprue
7320876	Phytase-containing animal food and method
7320998	Carbohydrate analog inhibitors of alpha-amylase
7329424	Process for manufacturing cheeses and other dairy products and products thereof
7329529	Ubiqutin proteases
→View more patents.

BioPortfolio Ltd. offers e-mail and postal lists for Lactase scientists - we have details of around 232 individuals working on Lactase .

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.  See User Agreement

Send comments and feedback to:
Peter Barfoot Managing Director, BioPortfolio Ltd.
UK Tel: (+44) 1300 321501
USA Voicemail and Fax: (+1) 415 680 2472

All rights reserved. All other trademarks recognized.

BioPortfolio Limited is registered in England & Wales at Wessex Barn, Dorchester Road, Frampton, Dorset, DT2 9NB, UK. No.3312883 VAT No. GB 744 6483 10

Copyright 1997-2008 - BioPortfolio Limited.