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Lactoylglutathione Lyase

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Recent Publications on Lactoylglutathione Lyase:

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Crystalline silica Min-U-Sil 5 induces oxidative stress in human bronchial epithelial cells BEAS-2B by reducing the efficiency of antiglycation and antioxidant enzymatic defenses.
Reactive oxygen species (ROS) play an important role as mediators of...
30th October, 2009
Department of Experimental Medicine, University of Perugia, via del Chem Biol Interact. 2009 Nov 10;182(1):13-21. Epub 2009 Aug 11.
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Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Preeclampsia is characterized by vascular endothelial dysfunction partly...
21st October, 2009
Department of Physiology, University of Alberta, Edmonton, Alberta, Hypertension. 2009 Oct;54(4):897-904. Epub 2009 Aug 17.
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Inhibition of glyoxalase I: the first low-nanomolar tight-binding inhibitors.
A series of rational modifications to the structure of known...
22nd September, 2009
Center for Drug Design, Academic Health Center, and Department of J Med Chem. 2009 Aug 13;52(15):4650-6.
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CYP17, GSTP1, PON1 and GLO1 gene polymorphisms as risk factors for breast cancer: an Italian case-control study.
BACKGROUND: Estrogens, environmental chemicals with carcinogenic...
19th September, 2009
Department of Experimental Medicine, University of Perugia, Perugia, BMC Cancer. 2009 Apr 20;9:115.
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Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies.
OBJECTIVES: Methylglyoxal is a major precursor in the formation of...
16th September, 2009
Cardiovascular Research Institute Maastricht (CARIM), Maastricht J Hypertens. 2009 Jul;27(7):1399-403.
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Lactoylglutathione Lyase Patents:

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US Patent No.Title
7524504 Anti-glycation hydrolysate of G. lucidum
6479055 Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
6395299 Matrices for drug delivery and methods for making and using the same
6228983 Human respiratory syncytial virus peptides with antifusogenic and antiviral activities
6093794 Isolated peptides derived from the Epstein-Barr virus containing fusion inhibitory domains

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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