Lamivudine

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor .It is marketed by GlaxoSmithKline with the brand names Zeffix, Epivir, and Epivir-HBV.Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus mutant. Despite this, lamivudine is still used widely as it is well tolerated. (From the Wikpedia article Lamivudine.)

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Recent Publications on Lamivudine:
Mortality and drug exposure in a 5-year cohort of patients with chronic liver disease. BACKGROUND: Chronic liver diseases are common in the general population....	20th November, 2009	Division of General Internal Medicine, Brigham and Women's Hospital,	Swiss Med Wkly. 2009 Nov 19. DOI Direct Link
Treatment of HIV infection: Swedish recommendations 2009. On 4 previous occasions, in 2002, 2003, 2005 and 2007, the Swedish Medical...	20th November, 2009	From the Department of Clinical Pharmacology, Karolinska University	Scand J Infect Dis. 2009;41(11-12):788-807.
Progress in basic and clinical research on HIV resistance: report on the XVIII International HIV Drug Resistance Workshop. Over nearly two decades, the International HIV Drug Resistance Workshop...	18th November, 2009	Allentown, PA, USA.	Antivir Ther. 2009;14(7):1015-37. DOI Direct Link
Evolution of hepatitis B virus mutation during entecavir rescue therapy in patients with antiviral resistance to lamivudine and adefovir. BACKGROUND: The efficacy of entecavir (ETV) monotherapy in...	18th November, 2009	Department of Internal Medicine, Konkuk University School of Medicine,	Antivir Ther. 2009;14(7):985-93. DOI Direct Link
Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy. BACKGROUND:: Pregnancy-limited antiretroviral therapy (PLAT) drastically...	17th November, 2009	aBrigham and Women's Hospital, Harvard Medical School, Boston,	AIDS. 2009 Nov 12. DOI Direct Link
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Press Releases About Lamivudine:
Bristol-Myers Squibb Welcomes NICE Guidance Recommending Baraclude(R) (entecavir) as a Treatment Option for Chronic Hepatitis B	29th August, 2008		UXBRIDGE, England, August 29 /PRNewswire/ -- NICE (National Institute for Health and Clinical Excellence) has published guidance that recommends Baraclude(R) (entecavir) as an option for treatment of
Chronic viral hepatitis: B is for billions	1st March, 2005	Datamonitor	Chronic viral hepatitis: B is for billions Despite recent advances in the treatment and management of hepatitis B, the market is still relatively immature, with several key unmet needs.

BioNews Results for Lamivudine:
Review Finds Pegylated Interferon Is More Effective than Lamivudine for Chronic Hepatitis B, but Study Shows L	HIV and Hepatitis.com:  Nov 18 2009 4:42AM Matching: lamivudine
Trends in Waiting List Registration for Liver Transplantation for Viral Hepatitis in the United States	National AIDS Treatment Advocacy Project:  Nov 7 2009 3:04AM Matching: lamivudine
HIV/AIDS Update - Tentative Approval of Lamivudine and Tenofovir DF Fixed Dose Combination Tablets, 300mg/300m	Pharma Live:  Nov 7 2009 2:57AM Matching: lamivudine
Adefovir Plus Lamivudine Is Effective in Patients With Lamivudine-Resistance Chronic Hepatitis B: Presented at	Doctors Guide:  Nov 2 2009 11:18PM Matching: lamivudine
Lamivudine, Entecavir Both Improved Prognosis in Hepatitis B-Related Acute-on-Chronic Liver Failure: Presented	Doctors Guide:  Nov 2 2009 11:18PM Matching: lamivudine
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Lamivudine Patents:
US Patent No.	Title
7589204	Indane compounds as CCR5 antagonists
7598029	Method for identifying HIV-1 protease inhibitors with reduced metabolic affects
7598235	Bile-acid conjugates for providing sustained systemic concentrations of drugs
7598248	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
7598264	HIV integrase inhibitors
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Companies working in the area of Lamivudine from Bioportfolio's Biocorporate database :
Company Name
Jinan Lekangxin Pharmacy Co.,Ltd We are pleased to introduce our company, Jinan Lekangxin Pharmacy Co., Ltd as one of the leading producer and exporters of APIs(active pharmaceutical ingredients) and intermediates in China.Presently... www.jnjz.com        View full profile
Flavoxate, Raltitrrexed sale We are pleased to introduce our company, Jinan Lekangxin Pharmacy Co., Ltd as one of the leading producer and exporters of APIs(active pharmaceutical ingredients) and intermediates in China.Presently...         View full profile

BioPortfolio Ltd. offers e-mail and postal lists for Lamivudine scientists - we have details of around 501 individuals working on Lamivudine .