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LamivudineLamivudine is a potent nucleoside analog reverse transcriptase inhibitor .It is marketed by GlaxoSmithKline with the brand names Zeffix, Epivir, and Epivir-HBV.Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus mutant. Despite this, lamivudine is still used widely as it is well tolerated. (From the Wikpedia article Lamivudine.) Download PDF 
Recent Publications on Lamivudine: |  |
Pretreatment alanine transaminase level may not be the most important predictor of hepatitis B envelope antigen loss in the older patient.
Background: Elevated pretreatment alanine aminotransferase (ALT) over two... | 19th July, 2008
| Department of Internal Medicine, Division of Gastroenterology, Inha
| Liver Int. 2008 Jul 10;.
DOI Direct Link |
New paradigms for the treatment of chronic hepatitis B.
The main goals of chronic hepatitis B treatment should be the long-term... | 19th July, 2008
| Department of Medicine, Queen Mary Hospital, The University of Hong Kong,
| J Gastroenterol Hepatol. 2008 Jun 10;.
DOI Direct Link |
Prediction value of model for end-stage liver disease scoring system on prognosis in patients with acute-on-chronic hepatitis B liver failure after plasma exchange and lamivudine treatment.
Background and Aim: We used the model for end-stage liver disease (MELD)... | 19th July, 2008
| Department of Infectious Diseases, Second Affiliated Hospital, Harbin
| J Gastroenterol Hepatol. 2008 Jun 10;.
DOI Direct Link |
Initiation of hepatitis B virus genome replication and production of infectious virus following delivery in HepG2 cells by novel recombinant baculovirus vector.
One of the major problems in gaining further insight into hepatitis B... | 18th July, 2008
| INSERM, U871, 151 Cours Albert Thomas, 69003 Lyon, France.
| J Gen Virol. 2008 Aug;89(Pt 8):1819-28.
DOI Direct Link |
Prediction of phenotypic susceptibility to antiretroviral drugs using physiochemical properties of the primary enzymatic structure combined with artificial neural networks.
Objectives Genotypic interpretation systems extrapolate observed... | 18th July, 2008
| Copenhagen HIV Programme, Faculty of Health Sciences, University of
| HIV Med. 2008 Jul 2;.
DOI Direct Link |
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Companies working in the area of Lamivudine from Bioportfolio's Biocorporate database : |  |
| Company Name | |
We are pleased to introduce our company, Jinan Lekangxin Pharmacy Co., Ltd as one of the leading producer and exporters of APIs(active pharmaceutical ingredients) and intermediates in China.Presently...
www.jnjz.com View full profile
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We are pleased to introduce our company, Jinan Lekangxin Pharmacy Co., Ltd as one of the leading producer and exporters of APIs(active pharmaceutical ingredients) and intermediates in China.Presently...
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. |