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LeishmaniasisLeishmaniasis is a disease caused by protozoan parasites that belong to the genus Leishmania and is transmitted by the bite of certain species of sand fly, including flies in the genus Lutzomyia in the New World and Phlebotomus in the Old World. The disease was named in 1901 for the Scottish pathologist William Boog Leishman. This disease is also known as Leichmaniosis, Leishmaniose, leishmaniose, and formerly, Orient Boils, Baghdad Boil, kala azar, black fever, sandfly disease, Dum-Dum fever or espundia.Most forms of the disease are transmissible only from animals , but some can be spread between humans. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani complex with three species ; the L. mexicana complex with 3 main species ; L. tropica; L. major; L. aethiopica; and the subgenus Viannia with four main species braziliensis, L. guyanensis, L. panamensis, and L. peruviana). The different species are morphologically indistinguishable, but they can be differentiated by isoenzyme analysis, DNA sequence analysis, or monoclonal antibodies. Visceral leishmaniasis is a severe form in which the parasites have migrated to the vital organs. (From the Wikpedia article Leishmaniasis.) Download PDF containing detailed information.
Recent Publications on Leishmaniasis: |  |
Structure of cyclophilin from Leishmania donovani bound to cyclosporin at 2.6 A resolution: correlation between structure and thermodynamic data.
Drug development against Leishmania donovani, the pathogen that causes... | 20th November, 2009
| Crystallography and Molecular Biology Division, Saha Institute of Nuclear
| Acta Crystallogr D Biol Crystallogr. 2009 Nov 1;65(Pt 11):1187-1195. Epub
DOI Direct Link |
Asymptomatic Leishmania infantum infection in a traditionally non-endemic area of North-western Italy (Piemonte region).
The prevalence of Leishmania infantum specific antibodies and asymptomatic... | 20th November, 2009
| Department of Clinical and Biological Sciences, University of Torino,
| J Clin Microbiol. 2009 Nov 18.
DOI Direct Link |
Enhanced Susceptibility to Leishmania Infection in Resistant Mice in the Absence of Immediate Early Response Gene X-1.
Immediate early response gene X-1 (IEX-1) is a stress-inducible gene... | 20th November, 2009
| Wellman Center for Photomedicine, Massachusetts General Hospital,
| J Immunol. 2009 Nov 18.
DOI Direct Link |
[Multifocal cutaneous leishmaniasis due to Leishmania infantum under adalimumab therapy.]
Immediate early response gene X-1 (IEX-1) is a stress-inducible gene... | 18th November, 2009
| Service de dermatologie, hopital Henri-Mondor, 51, avenue du
| Ann Dermatol Venereol. 2009 Nov;136(11):815-6. Epub 2009 Oct 9.
DOI Direct Link |
The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.
Miltefosine is currently marketed for treatment of skin metastasis of... | 18th November, 2009
| Department of Pharmacology, Toxicology, and Pharmacy, University of
| Eur J Pharmacol. 2009 Nov 13.
DOI Direct Link |
→View more research publications. |
Press Releases About Leishmaniasis:
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| New Consortium to Develop Drugs for Neglected Tropical Diseases |
17th August, 2009 |
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LEIDEN, The Netherlands, August 17 /PRNewswire/ -- A new consortium has been formed to boost drug development for the
treatment of two deadly diseases, African sleeping sickness and
Leishmaniasis,
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| IDRI Collaborates with the Brazilian Butantan Institute To Develop Novel Vaccines Against Leishmaniasis |
22nd January, 2009 |
IDRI |
SEATTLE, Jan. 22 /PRNewswire/ -- IDRI (Infectious Disease Research
Institute) announced it has granted the Instituto Butantan, a Brazilian
biomedical research institution, an exclusive license in
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| Max Planck Society Awards Exclusive License to Dafra Pharma R&D to Develop a Drug Against Leishmaniasis |
16th July, 2008 |
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TURNHOUT, Belgium, July 16 /PRNewswire/ -- Max Planck Innovation, the technology transfer agency of the
Max Planck Society based in Munich, Germany and Dafra Pharma R&D, a Belgian
research company
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| Institute for OneWorld Health Completes Patient Enrollment, Treatment In
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1st January, 1970 |
Institute Of One World |
Institute
for OneWorld Health Completes Patient Enrollment, Treatment In India for Largest
Phase III Clinical Trial for Visceral Leishmaniasis (Kala Azar)
San
Francisco, Calif. – May 18
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Companies working in the area of Leishmaniasis from Bioportfolio's Biocorporate database : | |
| Company Name | |
In January 2004, Astralis Ltd received its first patent from the United States Patent Office. This achievement has resulted from the quality and focus of our therapeutic research and development....
www.astralisltd.com/ View full profile
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InBios International, Inc. is a medical diagnostic company that specializes in developing, manufacturing and marketing medical diagnostic tests for the detection of infectious diseases. Since its...
www.inbios.com/ View full profile
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LICA Pharmaceuticals and Walter Reed Army Institute of Research, US Army, have entered into a joint research and development agreement on further development of LICA's antimalarial drug candidate ...
www.licapharma.com/ View full profile
| | →View more Leishmaniasis related companies. |
BioPortfolio Ltd. offers e-mail and postal lists for Leishmaniasis scientists - we have details of around 1401 individuals working on Leishmaniasis .
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
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