Lipogenesis

Lipogenesis is the process by which glucose is converted to fatty acids, which are subsequently esterified to glycerol to form the triacylglycerols that are packaged in VLDL and secreted from the liver.Lipogenesis encompasses the processes of fatty acid synthesis and subsequent triglyceride synthesis.Lipogenesis starts with acetyl-CoA and builds up by the addition of two carbons units. The synthesis occurs in the cytoplasm in contrast to the degradation which occurs in the mitochondria. Many of the enzymes for the fatty acid synthesis are organized into a multienzyme complex called fatty acid synthetase . (From the Wikpedia article Lipogenesis.)

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Recent Publications on Lipogenesis:
The homeodomain protein HOXB13 regulates the cellular response to androgens. HOXB13 is a member of the homeodomain family of sequence-specific...	18th November, 2009	Department of Pharmacology and Cancer Biology, Duke University Medical	Mol Cell. 2009 Nov 13;36(3):405-16. DOI Direct Link
Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat. Excessive energy intake greatly contributes to the development of...	17th November, 2009	State Key laboratory of Medical Genomics and Shanghai Institute of	Metabolism. 2009 Nov 13. DOI Direct Link
Gene expression patterns in visceral and subcutaneous adipose depots in rats are linked to their morphologic features. The aim was to characterize the expression pattern of genes involved in...	17th November, 2009	University of the Balearic Islands, CIBER de Fisiopatologia de la Obesidad	Cell Physiol Biochem. 2009;24(5-6):547-56. Epub 2009 Nov 4. DOI Direct Link
Liver X receptor {alpha} regulates fatty acid synthase expression in chicken. Liver X receptor alpha (LXRalpha), also referred to as nuclear receptor...	12th November, 2009	INRA, UMR 598 Genetique Animale, F-35000 Rennes, France;	Poult Sci. 2009 Dec;88(12):2628-35. DOI Direct Link
Seasonal dynamics of clinically significant metabolic parameters in northern residents of different age. One-year monitoring of the blood metabolic parameters in residents of the...	11th November, 2009	Department of Ecological and Social Human Physiology, Institute of	Bull Exp Biol Med. 2009 Jun;147(6):757-9.
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Lipogenesis Patents:
US Patent No.	Title
7381433	Compositions containing an extract of a primula denticulata and use thereof
7452548	Conjugated linoleic acid compositions
7465710	Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm
7476731	Variants of the alpha 1 subunit of human AMPK
7479540	Adipomodulin and related molecules and methods
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