Malaria

Malaria is a vector-borne infectious disease caused by protozoan parasites. It is widespread in tropical and subtropical regions, including parts of the Americas, Asia, and Africa. Each year, it causes disease in approximately 515 million people and kills between one and three million people, the majority of whom are young children in Sub-Saharan Africa. Malaria is commonly associated with poverty, but is also a cause of poverty and a major hindrance to economic development.Malaria is one of the most common infectious diseases and an enormous public health problem. The disease is caused by protozoan parasites of the genus Plasmodium. Only four types of the plasmodium parasite can infect humans; the most serious forms of the disease are caused by Plasmodium falciparum and Plasmodium vivax, but other related species can also affect humans. This group of human-pathogenic Plasmodium species is usually referred to as malaria parasites.Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include symptoms of anemia , as well as other general symptoms such as fever, chills, nausea, flu-like illness, and in severe cases, coma and death. Malaria transmission can be reduced by preventing mosquito bites with mosquito nets and insect repellents, or by mosquito control measures such as spraying insecticides inside houses and draining standing water where mosquitoes lay their eggs.Although some are under development, no vaccine is currently available for malaria; preventative drugs must be taken continuously to reduce the risk of infection. These prophylactic drug treatments are often too expensive for most people living in endemic areas. Most adults from endemic areas have a degree of long-term recurrent infection and also of partial resistance; the resistance reduces with time and such adults may become susceptible to severe malaria if they have spent a significant amount of time in non-endemic areas. They are strongly recommended to take full precautions if they return to an endemic area. Malaria infections are treated through the use of antimalarial drugs, such as quinine or artemisinin derivatives, although drug resistance is increasingly common. (From the Wikpedia article Malaria.)

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Recent Publications on Malaria:
An autologous falciparum vaccine using the erythrocyte's band 3 molecule. Protection against the serious complications of falciparum malaria is...	21st November, 2009	Manatee Memorial Hospital, 206 2(nd) Street East, Bradenton, FL 34209,	Med Hypotheses. 2009 Nov 17. DOI Direct Link
Pharmacogenetics of antimalarial drugs: effect on metabolism and transport. The prevention and management of malaria is primarily based on the use of...	21st November, 2009	Pharmacogenetics, Dr Margarete Fischer-Bosch Institute of Clinical	Lancet Infect Dis. 2009 Dec;9(12):760-774. DOI Direct Link
Structure and mechanism in salivary proteins from blood-feeding arthropods. The saliva of blood-feeding arthropods contains rich mixtures of ligand...	21st November, 2009	Laboratory of Malaria and Vector Research, National Institute of Allergy	Toxicon. 2009 Nov 16. DOI Direct Link
Microparticle-mediated gene delivery for the enhanced expression of a 19-kDa fragment of merozoite surface protein 1 of Plasmodium falciparum. The 19 kDa carboxyl-terminal fragment of merozoite surface protein 1...	20th November, 2009	Bio Engineering Laboratory (BEL), Department of Chemical Engineering,	Biotechnol Prog. 2009 Nov 18. DOI Direct Link
Visualisation and Quantitative Analysis of the Rodent Malaria Liver Stage by Real Time Imaging. The quantitative analysis of Plasmodium development in the liver in...	20th November, 2009	Department of Medical Microbiology, Radboud University Nijmegen Medical	PLoS One. 2009 Nov 18;4(11):e7881. DOI Direct Link
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Press Releases About Malaria:
Artemisinin Resistance Threatens Efforts to Control Malaria	19th November, 2009	The American Society of Tropical Medicine and Hygiene	WASHINGTON, Nov. 19 /PRNewswire/ -- Evidence of resistance to the antimalarial drug artemisinin and its derivatives threatens efforts to control malaria in Southeast Asia, and experts fear artemisinin
Malaria Experts Call on Federal Government to Increase Support for Research and Development	18th November, 2009	The American Society of Tropical Medicine and Hygiene	WASHINGTON, Nov. 18 /PRNewswire-USNewswire/ -- While efforts to control and eliminate malaria have made great strides during the past five years, the looming specter of drug resistance heightens the
Relief Group Says Simple, Effective Tactic in Global AIDS Fight Also One of Most Neglected	10th November, 2009	World Vision	-- New report shows prevention efforts still not priority in most poor countries' health budgets -- Only 1 in 3 HIV-positive pregnant women gets treatment to prevent mother-to-child transmission
Video: Ugandan Youth Soccer Player and Malaria Survivor, Soccer Stars and Prominent Malaria Champions Launch United Against Malaria Campaign in New York	10th November, 2009	United Against Malaria	NEW YORK, Nov. 10 /PRNewswire/ -- Twelve-year-old Ugandan soccer star and malaria survivor Charles Ssali, together with Major League Soccer Commissioner Don Garber, is making a stop in New York today
GAA Congratulates President Obama on New U.S. World Leadership in Lifting the HIV Travel Ban	30th October, 2009	Global AIDS Alliance	WASHINGTON, Oct. 30 /PRNewswire-USNewswire/ -- The Global AIDS Alliance welcomes President Obama's announcement today to lift the 22 year-old U.S. travel and immigration ban on those living with

BioNews Results for Malaria:
Life Sciences: Research from University of Oxford, Wellcome Trust Center for Human Genetics yields new findings on life sciences	NewsRX:  Nov 21 2009 5:48AM Matching: malaria
News outlets examine malaria drug resistance, hope for malaria eradication in Africa	News-Medical.Net:  Nov 21 2009 4:34AM Matching: malaria
Antimalarial drug resistance endangers malarial control measures	News-Medical.Net:  Nov 20 2009 7:08AM Matching: malaria
Sanofi-aventis, MMV to launch largest antimalarial drug study	PharmaBiz:  Nov 20 2009 9:14AM Matching: malaria
Vaccines on Horizon for AIDS, Alzheimer's, herpes	PharmaceuticalProcessing:  Nov 20 2009 8:23PM Matching: malaria
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Malaria Patents:
US Patent No.	Title
7601844	Piperidinyl derivatives as modulators of chemokine receptor activity
7608425	Methods for protein expression in mammalian cells in serum-free medium
7608427	Polynucleotide encoding an IL-28B polypeptide
7608428	Polynucleotide encoding an IL-28B polypeptide
7608433	Method of detection of classical swine fever
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Companies working in the area of Malaria from Bioportfolio's Biocorporate database :
Company Name
GenVec GenVec, Inc. (NASDAQ: GNVC) is a biopharmaceutical company developing novel gene-based therapeutic drugs and vaccines. Each of our gene-based therapeutic product candidates use a common patent... www.genvec.com/        View full profile
CEL-SCI Corporation CEL-SCI Corporation is involved in the research and development of certain drugs and vaccines. CEL-SCI's first product, MULTIKINE(TM), manufactured using the Company's proprietary cell...         View full profile
Hollis-Eden Pharmaceuticals Hollis-Eden Pharmaceuticals is a development-stage pharmaceutical company, is engaged in the discovery, development and commercialization of products for the treatment of a number of targeted disease... www.holliseden.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Malaria scientists - we have details of around 4663 individuals working on Malaria .