Recent Publications on Mannosidases: |  |
Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
The N-glycosylation pathway is a target for pharmaceutical intervention in...
Direct Link | 4th October, 2008
| Ontario Cancer Institute, Canada.
|
Deletion of the msdS/AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatus.
alpha-Mannosidases play an important role in the processing of...
Direct Link | 18th September, 2008
| State Key Laboratory of Microbial Resources, Institute of Microbiology,
|
Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site.
Golgi alpha-mannosidase II (GMII) is a key glycosyl hydrolase in the...
Direct Link | 4th September, 2008
| Department of Medical Biophysics, University of Toronto, Toronto, ON,
|
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.
Enzyme inhibition through mimicry of the transition state is a major area...
Direct Link | 7th August, 2008
| Institute for Cell and Molecular Biosciences, The Medical School,
|
Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer.
Aliphatic and ethylene glycol esters of 5-aminolevulinic acid (ALA) are...
Direct Link | 29th July, 2008
| Institute of Chemistry, Neuchatel University, avenue de Bellevaux, P.O.
|
Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant.
Inhibition of Golgi alpha-mannosidase II (GMII), which acts late in the...
Direct Link | 25th July, 2008
| Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend
|
Triple arginines in the cytoplasmic tail of endomannosidase are not essential for type II membrane topology and Golgi localization.
Endomannosidase is a Golgi-localized endoglycosidase, which provides an...
Direct Link | 10th July, 2008
| Division of Cell and Molecular Pathology, Department of Pathology,
|
Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site.
Refining the chemical structure of functionalized pyrrolidine-based...
Direct Link | 5th July, 2008
| Laboratory of Glycochemistry and Asymmetric Synthesis, Ecole Polytechnique
|
Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Class I alpha-mannosidases (glycoside hydrolase family GH47) play key...
Direct Link | 31st May, 2008
| Program in Molecular Structure and Function, Research Institute, The
|
Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.
Limb girdle muscular dystrophy type 2D (LGMD2D, OMIM600119) is a genetic...
Direct Link | 23rd May, 2008
| Genethon, CNRS-FRE3018, Evry 91000, France.
|
Crystallization and preliminary X-ray study of native and selenomethionyl beta-1,4-mannanase AaManA from Alicyclobacillus acidocaldariusTc-12-31.
AaManA, a beta-1,4-mannanase from the thermoacidophile Alicyclobacillus...
Direct Link | 30th April, 2008
| State Key Laboratory of Microbial Resources, Institute of Microbiology,
|
| Influenza A (H1N1) virus resistance to cyanovirin-N arises naturally during adaptation to mice and by passage in cell culture in the presence of the inhibitor.
| 17th April, 2008
| Institute for Antiviral Research, Utah State University, Logan, UT, USA.
|
Effects of macromolecular crowding on glycoprotein processing enzymes.
Intracellular environments are highly crowded due to the presence of...
Direct Link | 9th April, 2008
| RIKEN, The Institute of Physical and Chemical Research, 2-1 Hirosawa,
|
| Cloning and strong expression of a Bacillus subtilis WL-3 mannanase gene in B. subtilis.
| 29th February, 2008
| School of Food Science & Biotechnology, Woosong University, Daejeon,
|
Microbial mannanases: an overview of production and applications.
Microbial mannanases have become biotechnologically important since they...
Direct Link | 13th February, 2008
| Department of Biotechnology, GGDSD College, Chandigarh, India.
|
