Recent Publications on Map Kinase Kinase 1: |  |
Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells.
MAPK pathways regulate transcription through phosphorylation of...
Direct Link | 1st October, 2008
| Department of Pharmacology, University of Texas Southwestern Medical
|
Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line.
BACKGROUND: In prostate cancer, the identification of drug combinations...
Direct Link | 27th September, 2008
| Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la
|
| Emdogain stimulates matrix degradation by osteoblasts.
| 19th September, 2008
| Departments of Biochemistry, Osaka Dental University, Osaka, Japan.
|
Retinoic acid induces apoptosis by a non-classical mechanism of ERK1/2 activation.
Even though RA is involved in differentiation and apoptosis of normal and...
Direct Link | 30th August, 2008
| Centro de Estudos em Estresse Oxidativo, Departamento de Bioquimica,
|
Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.
Gefitinib (Iressa(R), ZD1839) is a selective epidermal growth factor...
Direct Link | 20th August, 2008
| Department of Internal Medicine, Hsinchu Hospital, Department of Health,
|
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma.
Activating BRAF kinase mutations arise in approximately 7% of all human...
Direct Link | 19th August, 2008
| Center for Molecular Therapeutics, Massachusetts General Hospital Cancer
|
Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma.
Genetic lesions affecting a number of kinases and other elements within...
Direct Link | 7th August, 2008
| Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer
|
Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma.
Schwannomas are tumors of the nervous system that occur sporadically and...
Direct Link | 6th August, 2008
| Clinical Neurobiology, Peninsula College for Medicine and Dentistry,
|
| MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.
| 29th July, 2008
| Laboratory of Biological Protection, Department of Biological Responses,
|
Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells.
Mammalian cells express two closely related MEK isoforms, MEK1 and MEK2,...
Direct Link | 25th July, 2008
| Institute of Signaling Developmental Biology and Cancer, University of
|
| Hepatocyte growth factor promotes cell survival by phosphorylation of BAD in gastric cancer cells.
| 25th July, 2008
| Department of Hematology-Oncology, College of Medicine, Yeungnam
|
Differential regulation of rice mitogen activated protein kinase kinase (MKK) by abiotic stress.
Mitogen activated protein kinase cascade plays a crucial role in various...
Direct Link | 16th July, 2008
| National Institute for Plant Genome Research, Aruna Asaf Ali Road, New
|
| Specific properties of a C-terminal truncated androgen receptor detected in hormone refractory prostate cancer.
| 11th July, 2008
| Laboratoire de Cancerologie Experimentale et de Radiobiologie, Strasbourg,
|
| ERK/MAPK regulation of the androgen responsiveness of breast cancer cells.
| 11th July, 2008
| Department of Pathology, Royal Perth Hospital, Perth, Western Australia.
|
Tumour-mediated disruption of dendritic cell function: inhibiting the MEK1/2-p44/42 axis restores IL-12 production and Th1-generation.
Dysfunctional dendritic cells (DC) are common in cancer patients; however,...
Direct Link | 4th July, 2008
| Academic Unit of Clinical Oncology, University of Nottingham, City
|
