Recent Publications on Map Kinase Kinase 3: |  |
TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB.
Responses to transforming growth factor beta and multiple cytokines...
Direct Link | 30th August, 2008
| Center for Cell Signaling and Department of Microbiology, University of
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Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling.
Gram-positive bacterium Streptococcus pneumoniae is an important human...
Direct Link | 20th June, 2008
| Department of Microbiology and Immunology and Cardiovascular Research
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MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model.
In vitro studies have implicated activation of the p38 mitogen-activated...
Direct Link | 29th May, 2008
| Department of Nephrology, Monash Medical Centre, Clayton, Vic, Australia.
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Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction.
Tubulointerstitial fibrosis is a hallmark of chronic progressive kidney...
Direct Link | 9th May, 2008
| Department of Medicine, Renal Electrolyte Division, University of
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The Arabidopsis mitogen-activated protein kinase kinase MKK3 is upstream of group C mitogen-activated protein kinases and participates in pathogen signaling.
Although the Arabidopsis thaliana genome contains genes encoding 20...
Direct Link | 23rd April, 2008
| Department of Plant Molecular Biology, Max F. Perutz Laboratories,
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Mirk/Dyrk1B in cancer.
Mirk/Dyrk1B is a member of a conserved family of serine/threonine kinases...
Direct Link | 29th March, 2008
| Pathology Department, Upstate Medical University, State University of New
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MKK3-p38 signaling promotes apoptosis and the early inflammatory response in the obstructed mouse kidney.
Activation of the p38 mitogen-activated protein kinase (MAPK) pathway...
Direct Link | 19th December, 2007
| Department of Nephrology, Monash Medical Centre, 246 Clayton Rd., Clayton,
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MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.
The MAPK kinase kinase MEKK4 is required for neurulation and skeletal...
Direct Link | 13th December, 2007
| Department of Pharmacology and the Lineberger Comprehensive Cancer Center,
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Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.
Streptococcus pneumoniae (S. pneumoniae) causes high early mortality in...
Direct Link | 14th November, 2007
| Department of Microbiology and Immunology, University of Rochester Medical
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Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms.
Previously, we identified five active phosphatidylinositol ether lipid...
Direct Link | 20th October, 2007
| Medical Oncology Branch, Center for Cancer Research, NCI, National
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IL-12/23p40-dependent clearance of Anaplasma phagocytophilum in the murine model of human anaplasmosis.
Human anaplasmosis is an emerging infectious disease transmitted by ticks...
Direct Link | 25th September, 2007
| Section of Rheumatology, Department of Internal Medicine, Yale University
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A diacylglycerol kinase inhibitor, R59022, stimulates glucose transport through a MKK3/6-p38 signaling pathway in skeletal muscle cells.
Diacylglycerol kinase (DGK) is one of lipid-regulating enzymes, catalyzes...
Direct Link | 6th September, 2007
| Department of General Medicine, Asahikawa Medical College, 2-1-1-1,
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Metabolic stress signaling mediated by mixed-lineage kinases.
Saturated free fatty acid (FFA) is a major source of metabolic stress that...
Direct Link | 28th August, 2007
| Howard Hughes Medical Institute, University of Massachusetts Medical
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p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells.
PURPOSE: Increased expression of stromelysin-1 (matrix metalloproteinase...
Direct Link | 24th August, 2007
| Casey Eye Institute, Oregon Health & Science University, Portland, Oregon
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