Recent Publications on Map Kinase Kinase 5: |  |
Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization.
Twenty human proteins encode Phox/Bem1p (PB1) domains, which are involved...
Direct Link | 16th August, 2008
| Department of Pharmacology and the Lineberger Comprehensive Cancer Center,
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Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer.
Abnormal intracellular signaling contributes to carcinogenesis and may...
Direct Link | 7th August, 2008
| Urology Research Group, Northern Institute for Cancer Research, University
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Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.
The mitogen-activated protein kinases (MAPKs) ERK1/2, p38, and JNK are...
Direct Link | 23rd July, 2008
| Division of Immunology and Cancer Research Laboratory, Department of
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Ethylene signaling is required for the acceleration of cell death induced by the activation of AtMEK5 in Arabidopsis.
Mitogen-activated protein kinases (MAPKs) are involved in the regulation...
Direct Link | 17th July, 2008
| State Key Laboratory of Plant Physiology and Biochemistry, College of
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Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction.
Diabetes mellitus (DM) contributes to the exacerbation of left ventricle...
Direct Link | 13th June, 2008
| Cardiovascular Research Institute, University of Rochester School of
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Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells.
Steady laminar blood flow protects vessels from atherosclerosis. We showed...
Direct Link | 13th May, 2008
| Aab Cardiovascular Research Institute and Department of Medicine,
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HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway.
The ligand hepatocyte growth factor/scatter factor (HGF) and its receptor...
Direct Link | 29th March, 2008
| University of Vermont College of Medicine, Department of Pathology, 89
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Insight into the binding properties of MEKK3 PB1 to MEK5 PB1 from its solution structure.
MEKK3 is a mitogen-activated protein kinase kinase kinase that...
Direct Link | 6th March, 2008
| Hefei National Laboratory for Physical Sciences at Microscale and School
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| Big mitogen-activated protein kinase 1 (BMK1)/extracellular signal regulated kinase 5 (ERK5) is involved in platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell migration.
| 22nd February, 2008
| Department of Pharmacology, The University of Tokushima Graduate School of
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A genetic risk factor for periodic limb movements in sleep.
Big mitogen-activated protein kinase 1 (BMK1), also known as extracellular...
Direct Link | 30th January, 2008
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Aberrant extracellular signal-regulated kinase (ERK) 5 signaling in hippocampus of suicide subjects.
Extracellular signal-regulated kinase 5 (ERK5), the newest member of the...
Direct Link | 10th January, 2008
| Department of Psychiatry, Psychiatric Institute, University of Illinois at
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Fibroblast growth factor 13 is essential for neural differentiation in Xenopus early embryonic development.
In Xenopus embryonic development, the MEK5-ERK5 pathway, one of the MAPK...
Direct Link | 20th October, 2007
| Department of Cell and Developmental Biology, Graduate School of
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Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.
Restless legs syndrome (RLS) is a frequent neurological disorder...
Direct Link | 20th September, 2007
| Institute of Human Genetics, GSF National Research Center of Environment
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Noncanonical function of MEKK2 and MEK5 PB1 domains for coordinated extracellular signal-regulated kinase 5 and c-Jun N-terminal kinase signaling.
MEKK2 and MEK5 encode Phox/Bem1p (PB1) domains that heterodimerize with...
Direct Link | 10th July, 2007
| Department of Pharmacology, 1108 Mary Ellen Jones Building, University of
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Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors.
PURPOSE: The most well established molecular markers of poor outcome in...
Direct Link | 16th March, 2007
| Paediatric Oncology, Institute of Cancer Research/Royal Marsden NHS Trust,
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