Recent Publications on Map Kinase Kinase 6: |  |
ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo.
The pathways that allow quiescent disseminated cancer cells to survive...
Direct Link | 30th August, 2008
| Department of Biomedical Sciences, School of Public Health and Center for
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TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB.
Responses to transforming growth factor beta and multiple cytokines...
Direct Link | 30th August, 2008
| Center for Cell Signaling and Department of Microbiology, University of
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ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease.
Huntington's disease (HD) is an autosomal dominantly inherited...
Direct Link | 30th August, 2008
| Department of Human Genetics, Ruhr-University, 44780 Bochum, Germany.
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COX-2 promoter activation by AT1R-Gq-PAK-p38beta signaling in intestinal epithelial cells.
Cyclooxygenase-2 (COX-2) is rapidly induced by angiotensin (Ang)-II in the...
Direct Link | 20th August, 2008
| Department of Medicine, David Geffen School of Medicine, University of
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Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism.
NAG-1 (nonsteroidal anti-inflammatory drug-activated gene), a member of...
Direct Link | 19th July, 2008
| Eicosanoids Biochemistry Section, Laboratory of Molecular Carcinogenesis,
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Oligomeric beta-amyloid(1-42) induces the expression of Alzheimer disease-relevant proteins in cholinergic SN56.B5.G4 cells as revealed by proteomic analysis.
Alzheimer's disease (AD) is characterized by cholinergic dysfunction and...
Direct Link | 1st July, 2008
| Paul Flechsig Institute for Brain Research, University of Leipzig,
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Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.
Phosphoinositide signaling pathways regulate numerous processes in...
Direct Link | 21st May, 2008
| Department of Pharmacology, University of Wisconsin, Madison, WI 53706,
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Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.
During muscle regeneration, the mechanism integrating environmental cues...
Direct Link | 12th January, 2008
| The Burnham Institute for Medical Research, 10901 North Torrey Pines Road,
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c-Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin-based therapy.
Activation of p38 MAPK is a critical requisite for the therapeutics...
Direct Link | 9th January, 2008
| CRIB/Facultad de medicina, UCLM, 02006 Albacete, Spain.
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| Enhanced soluble production of biologically active recombinant human p38 mitogen-activated-protein kinase (MAPK) in Escherichia coli.
| 4th January, 2008
| Department of Biotechnology, Ranbaxy Research Laboratories, R&D -III, Plot
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MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts.
Phosphorylated p38 mitogen-activating kinase (MAPK) is observed in...
Direct Link | 22nd December, 2007
| Division of Hard Tissue Research, Institute for Oral Science, Matsumoto
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MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.
The MAPK kinase kinase MEKK4 is required for neurulation and skeletal...
Direct Link | 13th December, 2007
| Department of Pharmacology and the Lineberger Comprehensive Cancer Center,
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Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex.
The amyloid precursor protein (APP) is a type I transmembrane protein...
Direct Link | 13th December, 2007
| Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945,
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MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity.
Rac-dependent NADPH oxidases generate reactive oxygen species used in cell...
Direct Link | 8th December, 2007
| Department of Anatomy & Cell Biology, The University of Iowa, Iowa City,
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