Recent Publications on Map Kinase Kinase 7: |  |
Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPbeta-dependent pathway.
Shear stress is a pathophysiologically relevant mechanical signal in...
Direct Link | 1st August, 2008
| Department of Chemical and Biomolecular Engineering, The Johns Hopkins
|
Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin.
Transcriptional changes in response to hypoxia are regulated in part...
Direct Link | 26th July, 2008
| Abramson Family Cancer Center, University of Pennsylvania, 1020 BRB
|
GADD45B inhibits MKK7-induced cardiac hypertrophy and the polymorphisms of GADD45B is associated with inter-ventricular septum hypertrophy.
Mitogen-activated protein kinase kinase 7 (MKK7) induces cardiac...
Direct Link | 25th July, 2008
| Sino-German Laboratory for Molecular Medicine, FuWai Cardiovascular
|
Neuroprotection against ischemic brain injury by knockdown of hematopietic progenitor kinase 1 expression.
In this study, we investigated the role of hematopietic progenitor kinase...
Direct Link | 17th July, 2008
| Shanghai Institute of Materia Medica, Chinese Academy of Sciences,
|
PP2A regulates upstream members of the c-jun N-terminal kinase mitogen-activated protein kinase signaling pathway.
We have previously demonstrated that inhibition of the serine-threonine...
Direct Link | 12th July, 2008
| Division of Pediatric Critical Care Medicine, Cincinnati Children's
|
Requirements for PKC-augmented JNK activation by MKK4/7.
The c-Jun N-terminal kinases (JNKs) are activated in response to stress,...
Direct Link | 21st June, 2008
| Signal Transduction Program, The Burnham Institute for Medical Research,
|
Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.
The proinflammatory cytokine interleukin (IL)-1 activates several hundred...
Direct Link | 20th June, 2008
| Institute of Pharmacology, Medical School Hannover, D-30625 Hannover,
|
c-Jun is a negative regulator of myelination.
Schwann cell myelination depends on Krox-20/Egr2 and other promyelin...
Direct Link | 5th June, 2008
| Department of Anatomy and Developmental Biology, University College
|
Switching myelination on and off.
Schwann cells are remarkably plastic cells that can both form and stably...
Direct Link | 5th June, 2008
| Department of Cell Biology and Neurology, Smilow Neuroscience Program, New
|
Gadd45 beta forms a homodimeric complex that binds tightly to MKK7.
Gadd45 alpha, beta, and gamma proteins, also known as growth arrest and...
Direct Link | 15th May, 2008
| Dipartimento delle Scienze Biologiche, Istituto di Biostrutture e
|
Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism.
Mitogen-activated protein kinases (MAPKs) are key signaling molecules that...
Direct Link | 9th May, 2008
| Department of Pathology and the Arkansas Cancer Research Center,
|
Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation.
The c-Jun N-terminal kinase (JNK) signaling pathway plays a critical role...
Direct Link | 29th March, 2008
| Departement de Biologie Cellulaire et de Morphologie, Universite de
|
Overexpression of Arabidopsis MAP kinase kinase 7 leads to activation of plant basal and systemic acquired resistance.
There is a growing body of evidence indicating that mitogen-activated...
Direct Link | 20th March, 2008
| Department of Microbiology and Cell Science, University of Florida, P.O.
|
MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.
The MAPK kinase kinase MEKK4 is required for neurulation and skeletal...
Direct Link | 13th December, 2007
| Department of Pharmacology and the Lineberger Comprehensive Cancer Center,
|
Metabolic stress signaling mediated by mixed-lineage kinases.
Saturated free fatty acid (FFA) is a major source of metabolic stress that...
Direct Link | 28th August, 2007
| Howard Hughes Medical Institute, University of Massachusetts Medical
|
