Recent Publications on Map Kinase Kinase Kinase 3: |  |
Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation.
The protein kinase MEKK3 is essential for tumor necrosis factor alpha...
Direct Link | 18th June, 2008
| Department of Biology, York University, Toronto, Ontario M3J 1P3, Canada.
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Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signaling.
Several members of the mitogen-activated protein kinase kinase kinase...
Direct Link | 9th May, 2008
| Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
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Insight into the binding properties of MEKK3 PB1 to MEK5 PB1 from its solution structure.
MEKK3 is a mitogen-activated protein kinase kinase kinase that...
Direct Link | 6th March, 2008
| Hefei National Laboratory for Physical Sciences at Microscale and School
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The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.
In mice, targeted deletion of the serine protease HtrA2 (also known as...
Direct Link | 5th January, 2008
| Signal Transduction, Cancer Research UK London Research Institute, 44
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Proteomic identification of the cerebral cavernous malformation signaling complex.
Cerebral cavernous malformations (CCM) are sporadic or inherited vascular...
Direct Link | 3rd January, 2008
| Department of Pharmacology and the Lineberger Comprehensive Cancer Center,
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MEKK3 is required for endothelium function but is not essential for tumor growth and angiogenesis.
Mitogen-activated protein kinase kinase kinase 3 (MEKK3) plays an...
Direct Link | 14th December, 2007
| Department of Immunobiology, Yale University School of Medicine, New
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Hyperosmotic induction of mitogen-activated protein kinase scaffolding.
Eukaryotic cells respond to hyperosmotic conditions by expunging water...
Direct Link | 6th November, 2007
| Department of Pharmacology and Lineberger Comprehensive Cancer Center,
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MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages.
Mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a Ser/Thr protein...
Direct Link | 6th November, 2007
| Department of Immunology, The University of Texas, M. D. Anderson Cancer
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Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase.
The Sprouty (SPRY) family of proteins includes important regulators of...
Direct Link | 2nd August, 2007
| Department of Pathology, and Department of Mrfovs; Technology, Nagoya
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Zinc is a novel intracellular second messenger.
Zinc is an essential trace element required for enzymatic activity and for...
Direct Link | 29th June, 2007
| Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and
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IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms.
IL-20 is a novel member of the IL-10 cytokine family with pleiotropic...
Direct Link | 20th June, 2007
| Department of Dermatology, Aarhus University Hospital, Aarhus University,
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Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.
Interleukin-1 (IL-1) receptor-associated kinase (IRAK) is phosphorylated...
Direct Link | 19th June, 2007
| Department of Immunology, Cleveland Clinic Foundation, Cleveland, Ohio
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Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1.
In a normal stratified squamous epithelium, beta1-integrin is expressed in...
Direct Link | 15th December, 2006
| Institute of Pathology, Case Western Reserve University, 10900 Euclid Av.,
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MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells.
Mitogen-activated protein kinase (MAPK) cascades contain a trio of...
Direct Link | 27th October, 2006
| Renal Section, Department of Medicine, Baylor College of Medicine,
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TLR8-mediated NF-kappaB and JNK activation are TAK1-independent and MEKK3-dependent.
TLR8-mediated NF-kappaB and IRF7 activation are abolished in human...
Direct Link | 19th September, 2006
| Department of Immunology, Cleveland Clinic Foundation, Ohio 44195, USA.
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