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Map Kinase Kinase Kinase 4

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Recent Publications on Map Kinase Kinase Kinase 4:

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G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells.
In Drosophila, activation of Jun N-terminal Kinase (JNK) mediated by...		22nd May, 2008
Department of Pharmacology, Health Sciences Center, State University of J Cell Sci. 2008 Jan 15;121(Pt 2):234-45.
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Trouble making the first move: interpreting arrested neuronal migration in the cerebral cortex.
Postmitotic cortical neurons that fail to initiate migration can remain...		16th May, 2008
Department of Neurobiology and Kavli Institute of Neuroscience, Yale Trends Neurosci. 2008 Feb;31(2):54-61. Epub 2008 Jan 16.
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MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta.
The MAPK kinase kinase MEKK4 is required for neurulation and skeletal...		13th December, 2007
Department of Pharmacology and the Lineberger Comprehensive Cancer Center, J Biol Chem. 2007 Oct 19;282(42):30476-84. Epub 2007 Aug 28.
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Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia.
Identification of the signalling cascades that are differentially...		18th September, 2007
Department of Pathology, University of Chicago, Chicago, IL, USA. J Pathol. 2007 Aug;212(4):386-94.
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Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells.
Valproic acid (VPA), a mood stabilizer and anticonvulsant, has a variety...		27th June, 2007
Department of Pharmacology, National Research Institute for Child Health Exp Cell Res. 2007 May 15;313(9):1886-96. Epub 2007 Feb 28.
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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