Mastocytosis

Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells and CD34+ mast cell precursors in a person's body. (From the Wikpedia article Mastocytosis.)

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Recent Publications on Mastocytosis:
Successful treatment of KIT D816V-positive, imatinib-resistant systemic mastocytosis with interferon-alpha. We describe a case of systemic mastocytosis associated with...	17th November, 2009	Division of Hematology, Department of Internal Medicine, National Hospital	Intern Med. 2009;48(22):1973-8. Epub 2009 Nov 16.
Anaphylaxis: Recent advances in assessment and treatment. The incidence rate of anaphylaxis is increasing, particularly during the...	17th November, 2009	Department of Pediatrics, Faculty of Medicine, University of Manitoba,	J Allergy Clin Immunol. 2009 Oct;124(4):625-36; quiz 637-8. DOI Direct Link
On being metachromatic: Mystique and misunderstanding in mastocytosis. We describe a case of systemic mastocytosis associated with...	10th November, 2009	Department of Medicine, Division of Hematology, Stanford University School	Am J Hematol. 2009 Oct 23. DOI Direct Link
Expression of Activated STAT5 in Neoplastic Mast Cells in Systemic Mastocytosis. Subcellular Distribution and Role of the Transforming Oncoprotein KIT D816V. Recent data suggest that the signal transducer and activator of...	7th November, 2009	From the Department of Internal Medicine I,* Division of Hematology &	Am J Pathol. 2009 Nov 5. DOI Direct Link
Cytoreductive therapy in 108 adults with systemic mastocytosis: Outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine. Cytoreductive therapy in systemic mastocytosis (SM) includes several drugs...	6th November, 2009	Divisions of Hematology, Mayo Clinic, Rochester, Minnesota.	Am J Hematol. 2009 Oct 9. DOI Direct Link
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BioNews Results for Mastocytosis:
Pediatric Mastocytosis Is a Clonal Disease Associated with D816V and Other Activating c-KIT Mutations	Journal of Investigative Dermatology:  Oct 29 2009 10:51AM Matching: mastocytosis

Mastocytosis Patents:
US Patent No.	Title
7557106	Substituted pyrimidines useful as protein kinase inhibitors
7582629	Derivatives of isothiazol-3(2H)-one 1,1-dioxides as liver X receptor modulators
7582644	Pyrimidyl sulphone amide derivatives as chemokine receptor modulators
7582648	Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
7582654	Heterocyclo inhibitors of potassium channel function
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